Recombinant Mouse Tnip2 Protein, Myc/DDK-tagged
Cat.No. : | Tnip2-6561M |
Product Overview : | Purified recombinant protein of mouse full-length TNFAIP3 interacting protein 2 (cDNA clone MGC:62501 IMAGE:6404610), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells; promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 51.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Tnip2 TNFAIP3 interacting protein 2 [ Mus musculus (house mouse) ] |
Official Symbol : | Tnip2 |
Synonyms : | Tnip2; TNFAIP3 interacting protein 2; ABI; ABIN-2; AI428870; 1810020H16Rik; TNFAIP3-interacting protein 2; A20 binding inhibitor of NF-kappaB activation-2; A20-binding inhibitor of NF-kappa-B activation 2 |
Gene ID : | 231130 |
mRNA Refseq : | NM_139064 |
Protein Refseq : | NP_620703 |
UniProt ID : | Q99JG7 |
Products Types
◆ Recombinant Protein | ||
TNIP2-457H | Recombinant Human TNIP2 Protein, His-tagged | +Inquiry |
TNIP2-9488M | Recombinant Mouse TNIP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Tnip2-338M | Recombinant Mouse Tnip2 Protein, His-tagged | +Inquiry |
Tnip2-339R | Recombinant Rat Tnip2 Protein, His-tagged | +Inquiry |
TNIP2-17183M | Recombinant Mouse TNIP2 Protein | +Inquiry |
◆ Lysates | ||
TNIP2-888HCL | Recombinant Human TNIP2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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