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Recombinant Mouse Tph2 Protein, Myc/DDK-tagged

Cat.No. : Tph2-6595M
Product Overview : Purified recombinant protein of mouse full-length tryptophan hydroxylase 2 (Tph2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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  • Gene Information
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Description : Biased expression in cerebellum adult (RPKM 1.7), CNS E18 (RPKM 1.0) and 8 other tissues.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 55.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Tph2 tryptophan hydroxylase 2 [ Mus musculus (house mouse) ]
Official Symbol : Tph2
Synonyms : TPH2; tryptophan hydroxylase 2; tryptophan 5-hydroxylase 2; tryptophan 5-monooxygenase 2; neuronal tryptophan hydroxylase; Ntph; AU043594; MGC159133
Gene ID : 216343
mRNA Refseq : NM_173391
Protein Refseq : NP_775567
UniProt ID : Q8CGV2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How can TPH2 be targeted for therapeutic interventions? 09/25/2021

Targeting TPH2 through pharmacological agents or gene therapies may be explored to modulate serotonin levels and alleviate mood disorders.

What role does TPH2 play in anxiety disorders? 03/03/2021

TPH2 dysregulation may lead to imbalances in serotonin, contributing to the pathogenesis of anxiety disorders.

How does TPH2 relate to neurodegenerative disorders? 10/30/2019

TPH2 has been studied in the context of neurodegenerative disorders due to its influence on serotonin, which has neuroprotective properties.

Can TPH2 be a target for drug development in psychiatry? 05/16/2019

Yes, drugs targeting TPH2 or the serotonin pathway are being investigated for their potential in developing novel psychiatric medications.

Are there genetic factors influencing TPH2 expression? 01/28/2019

Yes, genetic variations can affect TPH2 expression, contributing to individual differences in serotonin levels and susceptibility to mood disorders.

Customer Reviews (3)

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Reviews
01/22/2021

    Its consistent and accurate results, combined with its compatibility with various cutting-edge techniques, ensure that data collection and analysis are both reliable and meaningful.

    11/10/2018

      The TPH2 protein's exceptional performance in ELISA and its successful application in protein electron microscopy structure analysis make it a highly reliable and recommended choice for researchers.

      01/24/2018

        The manufacturer's commitment to delivering a high-quality product further enhances its reputation and guarantees its suitability for a wide range of research applications.

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