Recombinant Mouse Tpt1, His-tagged

• Cat.No.: Tpt1-70M
• Product Overview: Recombinant mouse Tpt1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Description: Tpt1 also known as Translationally-controlled tumor protein. TPT1 is regulated at the translational level. This protein is involved in calcium binding and microtubule stabilization. It is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients.
• Form: Liquid. In Phosphate Buffered Saline containing 10% glycerol, 1mM DTT
• Molecular Mass: 22.1kDa (197aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMMIIYR DLISHDELFS DIYKIREIAD GLCLEVEGKM VSRTEGAIDD SLIGGNASAE GPEGEGTEST VVTGVDIVMN HHLQETSFTK EAYKKYIKDY MKSLKGKLEE QKPERVKPFM TGAAEQIKHI LANFNNYQFF IGENMNPDGM VALLDYREDG VTPFMIFFKD GLEMEKC
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: Tpt1 tumor protein, translationally-controlled 1 [ Mus musculus ]
• Official Symbol: Tpt1
• Synonyms: TPT1; tumor protein, translationally-controlled 1; translationally-controlled tumor protein; fortilin; translationally regulated transcript (21 kDa); 21 kDa polypeptide under translational control; Trt; p21; p23; TCTP
• Gene ID: 22070
• mRNA Refseq: NM_009429
• Protein Refseq: NP_033455
• Function: calcium ion binding; transcription factor binding