Recombinant Mouse Traf3ip1 Protein, Myc/DDK-tagged

• Cat.No.: Traf3ip1-6619M
• Product Overview: Purified recombinant protein of mouse full-length TRAF3 interacting protein 1 (Traf3ip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in epithelial morphogenesis and in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis.
• Molecular Mass: 71 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Traf3ip1 TRAF3 interacting protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Traf3ip1
• Synonyms: TRAF3IP1; TRAF3 interacting protein 1; TRAF3-interacting protein 1; microtubule-interacting protein associated with TRAF3; TNF receptor-associated factor 3 interacting protein 1; microtubule-interacting protein that associates with TRAF3; MIP-T3; AU041749; 3930402D05Rik; MGC143957
• Gene ID: 74019
• mRNA Refseq: NM_028718
• Protein Refseq: NP_082994
• UniProt ID: Q149C2