Recombinant Mouse Trim26 Protein, Myc/DDK-tagged

• Cat.No.: Trim26-6648M
• Product Overview: Purified recombinant protein of mouse full-length tripartite motif-containing 26 (Trim26), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.
• Molecular Mass: 62.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Trim26 tripartite motif-containing 26 [ Mus musculus (house mouse) ]
• Official Symbol: Trim26
• Synonyms: Trim26; tripartite motif-containing 26; Zfp17; Zfp173; Zfp1736; AI462198; tripartite motif-containing protein 26; tripartite motif protein 26; tripartite motif protein TRIM26; zinc finger protein 173; EC 2.3.2.27
• Gene ID: 22670
• mRNA Refseq: NM_001025599
• Protein Refseq: NP_001020770
• UniProt ID: Q99PN3