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Recombinant Mouse Tyk2 protein, His & T7-tagged

Cat.No. : Tyk2-7156M
Product Overview : Recombinant Mouse Tyk2 aa. (His667~Asp914 (Accession# Q9R117)) fused with N-terminal His & T7 tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Source : E. coli
Species : Mouse
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 31.2kDa
Protein length : His667~Asp914 (Accession# Q9R117)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.7.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Tyk2 tyrosine kinase 2 [ Mus musculus (house mouse) ]
Official Symbol : Tyk2
Synonyms : Tyk2; tyrosine kinase 2; JTK1; non-receptor tyrosine-protein kinase TYK2; tyrosine kinase TYK2
Gene ID : 54721
mRNA Refseq : NM_001205312.1
Protein Refseq : NP_001192241.1
UniProt ID : Q9R117

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Could TYK2 inhibitors have applications beyond autoimmune diseases? 05/14/2022

Yes, TYK2 inhibitors might have potential in treating certain cancers and possibly other inflammatory conditions beyond autoimmune diseases.

What are the potential benefits of targeting TYK2 in treating autoimmune diseases? 02/09/2021

TYK2 inhibition can potentially reduce inflammation and modulate immune responses without suppressing the entire immune system, unlike some other treatments.

Are there any clinical trials ongoing or completed regarding TYK2 inhibitors? 05/10/2020

Yes, there are several clinical trials evaluating the efficacy and safety of TYK2 inhibitors in various autoimmune diseases.

How do TYK2 inhibitors differ from other treatments for autoimmune diseases? 01/31/2018

TYK2 inhibitors are more targeted, aiming to interfere with specific signaling pathways involved in the immune response compared to broad immunosuppressants.

How are TYK2 inhibitors administered to patients? 11/17/2017

Depending on the formulation, TYK2 inhibitors can be administered orally or through injections.

Customer Reviews (3)

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Reviews
10/14/2022

    Their expertise in protein production and purification ensures the delivery of a high-quality product that consistently performs well in my experiments.

    06/15/2022

      They are readily available to address any concerns or questions and supply valuable resources to assist in experimental design and optimization.

      01/24/2018

        Should I encounter any challenges or require technical assistance, the manufacturer provides prompt and knowledgeable support.

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