Recombinant Mouse Ube2a Protein, Myc/DDK-tagged

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Recombinant Mouse Ube2a Protein, Myc/DDK-tagged

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Cat.No. : Ube2a-6779M
Product Overview : Purified recombinant protein of mouse full-length ubiquitin-conjugating enzyme E2A (Ube2a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 17.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Ube2a ubiquitin-conjugating enzyme E2A [ Mus musculus (house mouse) ]
Official Symbol : Ube2a
Synonyms : UBE2A; ubiquitin-conjugating enzyme E2A, RAD6 homolog (S. cerevisiae); ubiquitin-conjugating enzyme E2 A; RAD6 homolog A; ubiquitin-protein ligase A; ubiquitin carrier protein A; ubiquitin-conjugating enzyme HR6A; ubiquitin-conjugating enzyme E2A (RAD6 homolog); HR6A; HHR6A; Mhr6a
Gene ID : 22209
mRNA Refseq : NM_019668
Protein Refseq : NP_062642
UniProt ID : Q9Z255
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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