Recombinant Mouse Usp44 Protein, Myc/DDK-tagged
Cat.No. : | Usp44-6880M |
Product Overview : | Purified recombinant protein of mouse full-length ubiquitin specific peptidase 44 (Usp44), transcript variant 2, with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B (H2BK120ub1) ubiquitination. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 58 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Usp44 ubiquitin specific peptidase 44 [ Mus musculus (house mouse) ] |
Official Symbol : | Usp44 |
Synonyms : | Usp44; ubiquitin specific peptidase 44; E430004F17Rik; ubiquitin carboxyl-terminal hydrolase 44; deubiquitinating enzyme 44; inactive deubiquitinating enzyme 44; inactive ubiquitin carboxyl-terminal hydrolase 44; inactive ubiquitin thioesterase 44; inactive ubiquitin-specific-processing protease 44; ubiquitin specific peptidase 49 pseudogene; ubiquitin thioesterase 44; EC 3.4.19.12 |
Gene ID : | 327799 |
mRNA Refseq : | NM_183199 |
UniProt ID : | Q8C2S0 |
Products Types
◆ Recombinant Protein | ||
USP44-0353H | Recombinant Human USP44 Protein (M1-S712), GST tagged | +Inquiry |
USP44-0354H | Recombinant Human USP44 Protein (M1-S712), Tag Free | +Inquiry |
USP44-10596Z | Recombinant Zebrafish USP44 | +Inquiry |
USP44-3630H | Recombinant Human USP44, GST-tagged | +Inquiry |
◆ Lysates | ||
USP44-455HCL | Recombinant Human USP44 293 Cell Lysate | +Inquiry |
USP44-454HCL | Recombinant Human USP44 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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