Recombinant Mouse Vps26c Protein, Myc/DDK-tagged

• Cat.No.: Vps26c-6934M
• Product Overview: Purified recombinant protein of Mouse VPS26 endosomal protein sorting factor C (Vps26c), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retriever and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 33 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Vps26c VPS26 endosomal protein sorting factor C [ Mus musculus (house mouse) ]
• Official Symbol: Vps26c
• Synonyms: Vps26c; VPS26 endosomal protein sorting factor C; Dc; Dsc; Dcra; Dscr3; AW538125; vacuolar protein sorting-associated protein 26C; DSCR3 arrestin fold containing; Down syndrome critical region gene 3; Down syndrome critical region gene A; Down syndrome critical region protein 3 homolog; Down syndrome critical region protein A homolog
• Gene ID: 13185
• mRNA Refseq: NM_007834
• Protein Refseq: NP_031860
• UniProt ID: O35075