Recombinant Mouse Zgpat Protein, Myc/DDK-tagged

• Cat.No.: Zgpat-7106M
• Product Overview: Purified recombinant protein of Mouse zinc finger, CCCH-type with G patch domain (Zgpat), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 56.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Zgpat zinc finger, CCCH-type with G patch domain [ Mus musculus (house mouse) ]
• Official Symbol: Zgpat
• Synonyms: ZGPAT; zinc finger, CCCH-type with G patch domain; zinc finger CCCH-type with G patch domain-containing protein; BC021513; 1500006I01Rik; MGC25688; MGC38468
• Gene ID: 229007
• mRNA Refseq: NM_144894
• Protein Refseq: NP_659143
• UniProt ID: Q8VDM1