Recombinant Norovirus GII.4 VP1 antigen
Cat.No. : | VP1-16N |
Product Overview : | Recombinant Norovirus GII.4 VP1 antigen produced in mammalian HEK293 cells. |
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Description : | Norovirus VP1 protein is the capsid protein of Norovirus. It is a 59kD glycoprotein with three key domains. The shell domain (S domain) contains elements essential for the formation of the icosahedron. The Protruding domain (P domain) is divided into sub-domains P1 and P2. P domain interacts in dimeric contacts that increase the stability of the capsid and form the protrusions on the virion. An hypervariable region in P2 is thought to play an important role in receptor binding and immune reactivity. |
Source : | HEK293T |
Species : | Norovirus GII.4 |
Protein length : | 1-539 aa |
Form : | Liquid |
Molecular Mass : | 59 kDa |
Purity : | Greater than 95% purity by SDS-PAGE. |
Storage : | Short Term Storage: 4 centigrade Long Term Storage: -80 centigrade Freezing: Can be frozen and thawed at least 5 times. |
Concentration : | 1.0 mg/ml, according to BCA test method using BSA standards. |
Storage Buffer : | 20mM Tris-HCl pH 7.8, 10mM NaCl. |
References : | Karst SM. (2010). Pathogenesis of noroviruses, emerging RNA viruses. Viruses.Mar;2(3):748-81. PMID: 21994656 Robilotti E, Deresinski S, Pinsky BA. (2015). Norovirus. Clin Microbiol Rev.Jan;28(1):134-64. PMID: 25567225 Centers for disease control and prevention: Norovirus, Clinical overview Centers for disease control and prevention: Norovirus, Burden of norovirus illness and outbreaks Takeda press release: Takeda initiates world's first norovirus vaccine field trial |
Gene Name : | ORF2 VP1 [ Norovirus GII ] |
Official Symbol : | VP1 |
Synonyms : | VP1; D9V40_gp2; ORF2 |
Gene ID : | 39105315 |
Protein Refseq : | YP_009518842.1 |
UniProt ID : | Q83884 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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