Recombinant Pig LIPC protein, His & GST-tagged
Cat.No. : | LIPC-7645P |
Product Overview : | Recombinant Pig LIPC aa. (Gln103~Tyr356 (Accession # B8XSI5)) fused with N-terminal His & GST tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Pig |
Tag : | His & GST |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 60.0kDa |
Protein length : | Gln103~Tyr356 (Accession # B8XSI5) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 8.6. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | LIPC lipase C, hepatic type [ Sus scrofa (pig) ] |
Official Symbol : | LIPC |
Synonyms : | lipase, hepatic; hepatic triacylglycerol lipase |
Gene ID : | 100233189 |
mRNA Refseq : | NM_001143714.1 |
Protein Refseq : | NP_001137186.1 |
UniProt ID : | B8XSI5 |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionGenetic variations in the LIPC gene can influence enzyme activity, impacting lipid metabolism. Certain variants are associated with an increased risk of metabolic disorders such as dyslipidemia and insulin resistance.
LIPC contributes to lipid homeostasis by breaking down lipids, regulating their levels in the bloodstream. Dysregulation of LIPC activity is associated with imbalances in lipid profiles and an increased risk of cardiovascular diseases.
The expression of the LIPC gene is influenced by various factors, including dietary fat intake, hormonal signals, and genetic predisposition. Transcriptional regulators and epigenetic modifications also play a role.
LIPC interacts with various proteins in lipid metabolism pathways. Disruptions in these interactions can lead to impaired lipid processing, contributing to metabolic disorders and cardiovascular diseases.
Techniques such as RT-PCR, Western blotting, and enzyme assays are commonly used to study LIPC expression and activity. Additionally, advanced methods like mass spectrometry provide insights into post-translational modifications.
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