Recombinant Rabbit PDCD1 Protein

• Cat.No.: PDCD1-701R
• Product Overview: Recombinant Rabbit PDCD1 protein without tag was expressed in HEK293.

Specification

• Species: Rabbit
• Source: HEK293
• Protein Length: 289
• Description: Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
• Form: Lyophilized
• Molecular Mass: 22.95 kDa
• AA Sequence: MRVPWAPWSLLWAMLQLSWWPGWLLDAQDRPWSPLTFSPAQATVPEGANVTFTCSFSNISEHFVLNWYRLSPSNQRDKLAAFPEDRSRQPQDSRFRITRLPDGSSFHMSGIGVRRNDSGIYLCGAISLYPLMQIKESPQVELTVTERLLEPSTAQPSPSPRPPGQLQGLLIGVPSVLVGVLLLLLLAWVLVAMCPRTTQEAEGPKSQDQPLEKPLALPGSTMDYGELDFQWREKTPEPPATSVPEQTEYATIVFPDGLGTSSPGRRGSTDCLRGPRPLRSEDGHCSWPL
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: LOC100343779 programmed cell death 1 [ Oryctolagus cuniculus (rabbit) ]
• Official Symbol: PDCD1
• Synonyms: LOC100343779; programmed cell death 1; PDCD1; programmed cell death protein 1
• Gene ID: 100343779
• mRNA Refseq: XM_051829402
• Protein Refseq: XP_051685362