Recombinant Rat AGTR1A Protein
Cat.No. : | AGTR1A-566R |
Product Overview : | Recombinant Rat AGTR1A full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Rat |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Agtr1a angiotensin II receptor, type 1a [ Rattus norvegicus ] |
Official Symbol : | AGTR1A |
Gene ID : | 24180 |
mRNA Refseq : | NM_030985.4 |
Protein Refseq : | NP_112247.2 |
MIM : | |
UniProt ID : | P25095 |
Products Types
◆ Recombinant Protein | ||
AGTR1A-222R | Recombinant Rat AGTR1A Protein, His (Fc)-Avi-tagged | +Inquiry |
AGTR1A-397M | Recombinant Mouse AGTR1A Protein, His (Fc)-Avi-tagged | +Inquiry |
Agtr1a-1768R | Recombinant Rat Agtr1a protein, His & GST-tagged | +Inquiry |
AGTR1A-1430M | Recombinant Mouse AGTR1A Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (10)
Ask a questionAGTR1A activation leads to vasoconstriction by stimulating smooth muscle cell contraction, thereby affecting vascular tone and blood pressure.
Techniques such as co-immunoprecipitation (Co-IP) or proximity-based assays like the fluorescence resonance energy transfer (FRET) can be utilized to investigate protein-protein interactions involving AGTR1A.
Angiotensin II is the primary ligand for AGTR1A, but there are also selective agonists and antagonists that can modulate its activity for research and therapeutic purposes.
Genetic polymorphisms in AGTR1A have been associated with variable responses to ARBs and other antihypertensive medications, affecting treatment outcomes.
Lab researchers can use techniques like phospho-specific antibodies, ELISA assays, or luciferase reporter assays to assess the activation and downstream signaling of AGTR1A pathways.
AGTR1A signaling has been implicated in insulin resistance, glucose metabolism, and the development of metabolic disorders such as obesity and diabetes.
AGTR1A activates various signaling pathways, including phospholipase C (PLC), protein kinase C (PKC), mitogen-activated protein kinases (MAPKs), and intracellular calcium release.
AGTR1A has extracellular domains and specific amino acid residues within the transmembrane region that facilitate angiotensin II binding and receptor activation.
AGTR1A is activated when angiotensin II binds to the receptor, leading to conformational changes that initiate intracellular signaling cascades.
High-throughput screening (HTS) methods, such as cell-based assays or binding assays using radiolabeled ligands, can be employed to identify and evaluate potential compounds targeting AGTR1A.
Customer Reviews (5)
Write a reviewThe customer service was fantastic—helpful, friendly, and made the ordering process a breeze!
Quick delivery and secure packaging ensured my recombinant proteins arrived in perfect condition.
Super impressed with the reliable recombinant proteins I received at such a reasonable cost
The stability of this protein is unparalleled. It remains intact and active even under challenging conditions, ensuring reliable and reproducible results.
Couldn't be happier with the high-quality recombinant proteins I got at such an amazing price.
Ask a Question for All AGTR1A Products
Required fields are marked with *
My Review for All AGTR1A Products
Required fields are marked with *
Inquiry Basket