Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Rat AGTR1A Protein

Cat.No. : AGTR1A-566R
Product Overview : Recombinant Rat AGTR1A full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rat
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Agtr1a angiotensin II receptor, type 1a [ Rattus norvegicus ]
Official Symbol : AGTR1A
Gene ID : 24180
mRNA Refseq : NM_030985.4
Protein Refseq : NP_112247.2
MIM :
UniProt ID : P25095

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (10)

Ask a question
How does AGTR1A influence vascular tone? 09/25/2020

AGTR1A activation leads to vasoconstriction by stimulating smooth muscle cell contraction, thereby affecting vascular tone and blood pressure.

How can protein-protein interactions involving AGTR1A be studied in the lab? 05/29/2020

Techniques such as co-immunoprecipitation (Co-IP) or proximity-based assays like the fluorescence resonance energy transfer (FRET) can be utilized to investigate protein-protein interactions involving AGTR1A.

Are there specific ligands or agonists for AGTR1A? 04/04/2020

Angiotensin II is the primary ligand for AGTR1A, but there are also selective agonists and antagonists that can modulate its activity for research and therapeutic purposes.

Can AGTR1A polymorphisms influence drug response? 02/05/2020

Genetic polymorphisms in AGTR1A have been associated with variable responses to ARBs and other antihypertensive medications, affecting treatment outcomes.

How can AGTR1A signaling pathways be investigated in the lab? 11/10/2019

Lab researchers can use techniques like phospho-specific antibodies, ELISA assays, or luciferase reporter assays to assess the activation and downstream signaling of AGTR1A pathways.

Can AGTR1A contribute to insulin resistance and metabolic disorders? 08/08/2019

AGTR1A signaling has been implicated in insulin resistance, glucose metabolism, and the development of metabolic disorders such as obesity and diabetes.

What signaling pathways are activated by AGTR1A? 03/17/2019

AGTR1A activates various signaling pathways, including phospholipase C (PLC), protein kinase C (PKC), mitogen-activated protein kinases (MAPKs), and intracellular calcium release.

What are the structural features of AGTR1A that allow ligand binding? 01/14/2019

AGTR1A has extracellular domains and specific amino acid residues within the transmembrane region that facilitate angiotensin II binding and receptor activation.

How is AGTR1A activated? 07/11/2018

AGTR1A is activated when angiotensin II binds to the receptor, leading to conformational changes that initiate intracellular signaling cascades.

What is the process for screening compounds targeting AGTR1A in the lab? 07/14/2010

High-throughput screening (HTS) methods, such as cell-based assays or binding assays using radiolabeled ligands, can be employed to identify and evaluate potential compounds targeting AGTR1A.

Customer Reviews (5)

Write a review
Reviews
07/22/2022

    The customer service was fantastic—helpful, friendly, and made the ordering process a breeze!

    09/18/2021

      Quick delivery and secure packaging ensured my recombinant proteins arrived in perfect condition.

      04/10/2021

        Super impressed with the reliable recombinant proteins I received at such a reasonable cost

        02/24/2021

          The stability of this protein is unparalleled. It remains intact and active even under challenging conditions, ensuring reliable and reproducible results.

          08/20/2020

            Couldn't be happier with the high-quality recombinant proteins I got at such an amazing price.

            Ask a Question for All AGTR1A Products

            Required fields are marked with *

            My Review for All AGTR1A Products

            Required fields are marked with *

            0

            Inquiry Basket

            cartIcon
            logo

            FOLLOW US

            Terms and Conditions        Privacy Policy

            Copyright © 2024 Creative BioMart. All Rights Reserved.

            Contact Us

            • /

            Stay Updated on the Latest Bioscience Trends