Recombinant Rat Angpt1 protein, His-tagged

• Cat.No.: Angpt1-539R
• Product Overview: Recombinant rat Angpt1 protein with a N-terminal 6xHis tag was expressed in Yeast.

Specification

• Description: Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.
• Source: Yeast
• Species: Rat
• Tag: His
• Molecular Mass: 57.4kDa
• AA Sequence: SNQRRSPENGGRRYNRIQHGQCAYT FILPEHDGNCRESATEQYNTNALQR DAPHVETDFSSQKLQHLEHVMENYT QWLQKLENYIVENMKSEMAQIQQNA VQNHTATMLEIGTSLLSQTAEQTRK LTDVETQVLNQTSRLEIQLLENSLS TYELEKQLLQQTNEILKIQEKNSLL EHKILEMEGKHKEELDTLKEEKENL QGLVTRQTFIIQELEKQLSRATSNN SVLQKQQLELMDTVHNLVSLCTKEV LLKGGKREEEKPFRDCADVYQAGFN KSGIYTIYFNNMPEPKKVFCNMDVN EGGWTVIQHREDGSLDFQRGWKEYK MGFGNPSGEYWLGNEFIFAITSQRQ YMLRIELMDWEGNRAYSQYDRFHIG NQKQNYRLYLKGHTGTAGKQSSLIL HGADFSTKDADNDNCMCKCALMLTG GWWFDACGPSNLNGMFYTAGQNHGK LNGIKWHYFKGPSYSLRSTTMMIRP LDF
• Purity: Greater than 90% as determined by SDS-PAGE.
• Stability: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Storage Buffer: Tris-based buffer, 50% glycerol

Gene Information

• Gene Name: Angpt1 angiopoietin 1 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Angpt1
• Synonyms: Angpt1; angiopoietin 1; Agpt; Agpt1; Ang-1; angiopoietin-1
• Gene ID: 89807
• mRNA Refseq: NM_053546
• Protein Refseq: NP_445998
• UniProt ID: O35460