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Recombinant Rat ARRDC4 Protein

Cat.No. : ARRDC4-805R
Product Overview : Recombinant Rat ARRDC4 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rat
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Arrdc4 arrestin domain containing 4 [ Rattus norvegicus ]
Official Symbol : ARRDC4
Gene ID : 293019
mRNA Refseq : NM_001047853.1
Protein Refseq : NP_001041318.1
MIM :
UniProt ID : Q7TP90

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (12)

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Are there any known protein partners or interaction networks associated with ARRDC4? 12/21/2021

ARRDC4 is known to interact with several proteins and participate in various protein-protein interaction networks. It has been reported to interact with G protein-coupled receptors (GPCRs), components of the endocytic machinery, and signaling molecules involved in receptor internalization and trafficking.

Are there any known post-translational modifications of ARRDC4? 06/14/2021

Yes, ARRDC4 can undergo post-translational modifications such as phosphorylation, ubiquitination, and acetylation. These modifications can regulate its stability, activity, and protein-protein interactions.

Have any drugs been developed to target ARRDC4? 03/16/2021

As of now, there are no known drugs specifically targeting ARRDC4. However, ongoing research or drug discovery efforts may identify compounds that can modulate its function or interactions in the future.

Does the expression of ARRDC4 change during disease progression or under pathological conditions? 03/04/2021

There is evidence to suggest that the expression of ARRDC4 can be altered during disease progression or under pathological conditions. For example, aberrant expression of ARRDC4 has been observed in certain cancers and cardiovascular diseases, indicating its potential role in disease pathogenesis.

Is ARRDC4 regulated by specific stimuli or signaling pathways? 01/27/2021

ARRDC4 expression and activity can be regulated by specific stimuli or signaling pathways. For example, phosphorylation events mediated by protein kinases can modulate its function and localization in response to specific stimuli.

Is there any evidence linking ARRDC4 to human diseases or disorders? 05/31/2020

Yes, accumulating evidence suggests that ARRDC4 may play a role in certain human diseases or disorders. Studies have implicated its involvement in the pathogenesis of cancers, cardiovascular diseases, neurological disorders, and autoimmune conditions.

Is ARRDC4 localized to specific cellular compartments? 05/03/2020

ARRDC4 can be found in multiple cellular compartments depending on the context. It has been observed in the cell membrane, endosomes, lysosomes, and cytoplasm. Its subcellular localization can vary based on the specific cellular processes it is involved in.

What tissues or cell types express ARRDC4? 04/13/2019

ARRDC4 is expressed in various tissues and cell types. mRNA expression profiling and immunohistochemistry studies have shown its presence in the brain, heart, liver, kidney, and immune cells.

Does ARRDC4 have any role in intracellular signaling pathways? 03/16/2018

Yes, ARRDC4 can modulate intracellular signaling pathways, particularly those involving GPCRs. It has been shown to regulate receptor internalization, desensitization, and recycling, thereby influencing downstream signaling events.

Are there any known genetic variants or mutations in ARRDC4 associated with diseases? 11/19/2017

The presence of genetic variants or mutations in ARRDC4 associated with diseases has not been extensively explored. Genetic association studies or sequencing analyses may reveal any potential links between ARRDC4 genetic variations and disease susceptibility or progression.

Does ARRDC4 play a role in embryonic development or tissue homeostasis? 06/28/2017

The involvement of ARRDC4 in embryonic development or tissue homeostasis is not well-characterized. Investigating its expression patterns and conducting functional studies in relevant models can provide insights into its potential roles during development and in maintaining tissue equilibrium.

Can ARRDC4 be used as a diagnostic or prognostic biomarker? 03/25/2016

Currently, the diagnostic or prognostic utility of ARRDC4 as a biomarker is not well-established. However, further investigations exploring its expression patterns and associations with disease parameters may elucidate its potential as a biomarker in specific conditions.

Customer Reviews (3)

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Reviews
05/31/2021

    The combination of the protein's exceptional characteristics and the manufacturer's outstanding technical assistance equips me with the necessary resources to overcome potential hurdles and achieve groundbreaking results.

    04/23/2019

      By relying on the ARRDC4 protein, I can approach my research with unwavering confidence in its quality and the unparalleled support extended by its manufacturer.

      03/07/2017

        Their expertise and responsiveness exemplify their dedication to assisting customers, offering solutions and guidance whenever challenges arise.

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