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Recombinant Rat Art4 protein, His & T7-tagged

Cat.No. : Art4-716R
Product Overview : Recombinant Rat Art4 aa. (Tyr51~Cys275 (Accession# F1MA10)) fused with N-terminal His & T7 tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Source : E. coli
Species : Rat
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 29.2kDa
Protein length : Tyr51~Cys275 (Accession# F1MA10)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 9.4.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Gene Name : Art4 ADP-ribosyltransferase 4 [ Rattus norvegicus (Norway rat) ]
Official Symbol : Art4
Synonyms : Art4; ADP-ribosyltransferase 4; ATR4; ecto-ADP-ribosyltransferase 4; ADP-ribosyltransferase 4 (Dombrock blood group); NAD(P)(+)--arginine ADP-ribosyltransferase
Gene ID : 312806
mRNA Refseq : NM_001173509.1
Protein Refseq : NP_001166980.1
UniProt ID : F1MA10

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Does ART4 have any non-enzymatic functions or interactions with other proteins? 01/13/2023

Beyond its enzymatic role in ADP-ribosylation, ART4 does not have well-characterized non-enzymatic functions or specific protein interactions.

How does ART4 catalyze ADP-ribosylation? 05/18/2021

ART4 transfers ADP-ribose from NAD+ to specific target proteins, modifying their structure and function.

Are there any known diseases or disorders associated with mutations in the ART4 gene? 12/19/2019

Mutations in the ART4 gene are not commonly associated with diseases or disorders in humans.

Are there any therapeutic applications targeting ART4? 06/21/2019

ART4 itself is not targeted therapeutically. However, understanding its role in blood group antigen regulation may have implications in blood transfusion medicine and compatibility testing.

What are some known substrates of ART4? 11/26/2018

ART4 ADP-ribosylates specific glycoproteins on the surface of red blood cells, such as the P1 and P2 antigens.

Is the activity of ART4 influenced by any cofactors or regulators? 05/27/2017

ART4 activity depends on the availability of NAD+ as a substrate, and it may also be regulated by cellular signaling pathways related to red blood cell function.

Customer Reviews (3)

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Reviews
01/04/2023

    With its remarkable purity and reliability, coupled with the manufacturer's excellent technical support, this protein is a crucial asset in addressing my scientific inquiries and advancing my research goals.

    06/17/2017

      In addition to its outstanding quality, the Art4 Protein exhibits exceptional stability during storage and usage.

      04/07/2016

        Their team of experts has been instrumental in addressing any issues or concerns I have encountered during my experiments.

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