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Recombinant Rat CD3e Protein, Fc-tagged

Cat.No. : CD3e-1115R
Product Overview : Recombinant rat Cd3e (NP_001101610.1) (Tyr24-Asp103) was expressed with the Fc region of human IgG1 at the C-terminus.
  • Specification
  • Gene Information
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Source : HEK293
Species : Rat
Tag : Fc
Predicted N Terminal : Tyr 24
Form : Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
Molecular Mass : The recombinant rat Cd3e consists 318 amino acids and predicts a molecular mass of 36.1 kDa.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >95 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : Cd3e CD3 molecule, epsilon [ Rattus norvegicus ]
Official Symbol : CD3e
Synonyms : CD3E; CD3 molecule, epsilon; T-cell surface glycoprotein CD3 epsilon chain; CD3 antigen, epsilon polypeptide; CD3 molecule, epsilon polypeptide;
Gene ID : 315609
mRNA Refseq : NM_001108140
Protein Refseq : NP_001101610
MIM :
UniProt ID :
Pathway : Adaptive Immune System, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Dow
Function : SH3 domain binding; SH3 domain binding; molecular_function; protein heterodimerization activity; protein heterodimerization activity; signal transducer activity; signal transducer activity; transmembrane signaling receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can CD3E be used to assess the effectiveness of cancer immunotherapies? 04/07/2021

Yes, CD3E levels and T-cell function can be monitored to evaluate the response to cancer immunotherapies like checkpoint inhibitors.

Are there any CD3E-targeted therapies? 06/01/2017

There are currently no approved therapies that directly target CD3E, but it is a target for research in developing immunotherapies and cancer treatments.

Are there any ongoing clinical trials involving CD3E? 12/20/2016

There may be ongoing clinical trials using CD3E-targeted therapies in the context of cancer and autoimmune diseases. It's important to check clinical trial databases for specific studies.

Can CD3E levels be used to monitor the progression of HIV? 08/27/2016

Yes, monitoring CD3E levels in HIV-infected individuals can provide valuable information about the progression of the disease and the effectiveness of antiretroviral therapy.

How is CD3E used in allergy diagnostics? 06/22/2016

CD3E can be used in research to study T-cell responses in allergic conditions, helping to better understand and diagnose allergies.

Customer Reviews (3)

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Reviews
03/22/2023

    Manufacturers with the capacity for bulk production can offer CD3E protein in larger quantities, which is advantageous for researchers working on large-scale experiments or collaborations.

    09/12/2021

      bulk production often leads to economies of scale, making the CD3E protein more cost-effective for research budgets.

      06/17/2018

        Manufacturers can actively seek collaborations and partnerships with researchers to develop new applications or optimize methodologies using CD3E protein.

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