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Recombinant Rat Cdk2 protein, His-tagged

Cat.No. : Cdk2-1937R
Product Overview : Recombinant Rat Cdk2 aa. (Ser94~Leu212 (Accession # Q63699)) fused with N-terminal His tag was produced in E. coli cells.
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  • Gene Information
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Source : E. coli
Species : Rat
Tag : His
Form : Freeze-dried powder
Molecular Mass : 15 kDa as determined by SDS-PAGE reducing conditions.
Protein length : Ser94~Leu212 (Accession # Q63699)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 95%
Characteristic : The isoelectric point is 7.2.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Cdk2 cyclin dependent kinase 2 [ Rattus norvegicus (Norway rat) ]
Official Symbol : Cdk2
Synonyms : MYO1C; myosin IC; NMI; MMIb; myr2; MMI-beta; unconventional myosin-Ic; myosin-I beta; myosin-Ic; nuclear myosin I
Gene ID : 362817
mRNA Refseq : NM_199501.1
Protein Refseq : NP_955795.1
UniProt ID : Q63699

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the primary role of CDK2 in cell cycle regulation? 07/10/2021

CDK2 is crucial for driving cells through the G1/S and S phases of the cell cycle.

What role does CDK2 play in cellular response to DNA damage? 05/04/2020

CDK2 helps in cell cycle arrest to allow DNA repair, preventing mutation accumulation.

What are the key regulatory mechanisms controlling CDK2 activity? 03/08/2020

CDK2 activity is controlled by cyclins, CDK inhibitors, and phosphorylation status.

How is dysregulation of CDK2 implicated in cancer development? 01/23/2020

CDK2 dysregulation can lead to uncontrolled cell proliferation, contributing to cancer.

Are there existing or potential therapeutic strategies targeting CDK2? 01/08/2020

Targeting CDK2 with specific inhibitors is explored as a potential cancer therapy strategy.

How is CDK2 activity linked to cell cycle checkpoints? 04/06/2019

It is integral to cell cycle checkpoints ensuring DNA integrity before replication.

How does CDK2 contribute to DNA replication? 02/13/2018

It phosphorylates proteins necessary for DNA replication initiation.

Customer Reviews (3)

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Reviews
04/14/2022

    Product met expectations, happy.

    03/22/2022

      High quality, reliable results.

      05/31/2021

        Outstanding performance, highly recommend.

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