Recombinant Rat Csf1 protein, His-KSI-tagged

• Cat.No.: Csf1-1342R
• Product Overview: Recombinant Rat Csf1 protein(Q8JZQ0)(156-360aa), fused with N-terminal His and KSI tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Rat
• Tag: N-His-KSI
• Protein length: 156-360aa
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 37.5 kDa
• AASequence: KNFLEKDWNIFSKNCNDSFAKCSSR DVVTKPDCNCLYPKATPSSDLASAS PHQPPAPSMAPLADLAWDDSQRTEG SSLLPSDLPLRIEDPGSAKQRPPRS TCQTLESTEQPNHEDPQPHPSAGAP IPGVEDIIESSMGTNWVLEEASGEA SEGFLTQERKFSPSNPVGGSIQAET DRPWARSASSPFPKLTEDQQPTNIT DTPLT
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: Csf1 colony stimulating factor 1 (macrophage) [ Rattus norvegicus ]
• Official Symbol: Csf1
• Synonyms: CSF1; colony stimulating factor 1 (macrophage); macrophage colony-stimulating factor 1; MCSF; CSF-1
• Gene ID: 78965
• mRNA Refseq: NM_023981
• Protein Refseq: NP_076471

Reviews

10/30/2017

The CSF1 protein is renowned for its exceptional quality and reliability, making it an ideal choice to fulfill my experimental requirements.

03/10/2017

With its high purity and stability, this protein ensures dependable and accurate results, which are crucial for the success of my research endeavors.

06/09/2016

Whether it is for investigating cellular pathways, studying protein functions, or exploring signaling cascades, the CSF1 protein offers unparalleled versatility and performance.

Q&As

How does CSF1 affect cancer progression?

CSF1 is implicated in tumor-associated macrophages, influencing tumor growth, invasion, and the tumor microenvironment.

What are the potential side effects of CSF1 therapy?

Side effects may include immune-related adverse events, inflammation, and alterations in white blood cell counts.

Can CSF1 therapy be combined with other treatments?

Yes, there is ongoing research on combining CSF1-targeted therapies with other immunotherapies or conventional treatments to enhance efficacy.

What are the challenges in developing CSF1-based therapies?

Challenges include maintaining the balance of immune responses, potential off-target effects, and variability in patient responses.

In what ways is CSF1 being researched for neurological disorders?

Studies are exploring its role in neuroinflammation, neuroprotection, and potential therapeutic interventions for conditions like Alzheimer's disease.