Recombinant Rat Ctsk Protein


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Recombinant Rat Ctsk Protein

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Cat.No. : Ctsk-440R
Product Overview : Recombinant Rat Ctsk Protein (115-329 aa) without tag was expressed in E. coli.
Description : Cathepsin K, a member of the papain cysteine proteinase family is the predominant proteinase responsible for the resorption of the bone matrix. Cathepsin cleaves proteins such as collagen type I, collagen type II and osteonectin, thereby playing a role in bone remodeling and resorption in osteoporosis, osteolytic bone metastasis and rheumatoid arthritis (Bromme and Okamoto, 1995; Drake, F. et al 1996; Bossard et al, 1996).
Source : E. coli
Species : Rat
Bio-activity : The specific activity is >500 mU/mg (1U = 1 μmole/min/mg) as measured by Cathepsin K Activity Assay Kit.
Molecular Mass : 23.5 kDa (115-329 aa)
Purity : ≥ 90% by SDS–PAGE analysis
Usage : For Research Use Only! Not For Use in Humans.
Storage : Store at -80 centigrade
Storage Buffer : 0.5 mg/mL solution in 25 mM Na2HPO4 and 500 mM NaCl (pH 7.0) with 50% glycerol.
Shipping : Dry Ice

M: Protein Marker
1: Rat Cathepsin K (2 μg)
2: Rat Cathepsin K (5 μg)
3: Rat Cathepsin K (10 μg)
4: Rat Cathepsin K (15 μg)

Activity :

Measurement of r-Cathepsin K activity by Cathepsin K Activity Assay Kit

Gene Name : Ctsk cathepsin K [ Rattus norvegicus (Norway rat) ]
Official Symbol : Ctsk
Synonyms : Ctsk; cathepsin K; cathepsin K; EC; CTSK; CTSO3; CTSO
Gene ID : 29175
mRNA Refseq : NM_031560
Protein Refseq : NP_113748
UniProt ID : O35186

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