Recombinant Rat CXCL9 (MIG)
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Cat.No. : | CXCL9-93R Optional Service: Optional requirements on this protein |
Product Overview : | Rat CXCL9/MIG was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified. |
Description : | Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family. It is also commonly known as Monokine Induced by Gamma interferon (MIG). CXCL9 (MIG) is a T-cell chemoattractant, which is induced by IFN-gamma. It is closely related to two other CXC chemokines -CXCL10 and CXCL11. There have been 17 different C-X-C chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the C-X-C motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive C-X-C chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. C-X-C chemokines that lack the ELR motif are chemoattractant for lymphocytes. CXCL9 (MIG) elicits its effects by binding to the cell surface chemokine receptor CXCR3. |
Source : | Yeast |
Species : | Rat |
Form : | Lyophilized |
Molecular Mass : | 12.0 kDa |
AA Sequence : | TLVIRNQRCS CISTSQGTFH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSARV KKLMKEWEKK ISQKKKQKRG KNHQRSKKTR KAKTPHHPES KKTA (104) |
Applications : | The rat CXCL9/MIG protein can be used in cell culture, as a CXCL9/MIG ELISA Standard, and as a Western Blot Control. |
Storage : | -20 C |
Gene Name : | Cxcl9 chemokine (C-X-C motif) ligand 9 [ Rattus norvegicus ] |
Official Symbol : | CXCL9 |
Synonyms : | CXCL9; chemokine (C-X-C motif) ligand 9; C-X-C motif chemokine 9; small inducible cytokine B9; monokine induced by gamma interferon; Mig; Scyb9; MGC105312; |
Gene ID : | 246759 |
mRNA Refseq : | NM_145672 |
Protein Refseq : | NP_663705 |
Pathway : | Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem; |
Function : | CXCR3 chemokine receptor binding; chemokine activity; |
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◆ Native Protein
CXCL9-30233TH | Native Human CXCL9 | +Inquiry |
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◆ Lysates
CXCL9-7165HCL | Recombinant Human CXCL9 293 Cell Lysate | +Inquiry |
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CXCL1Cxcl10CXCL11CXCL12CXCL13CXCL14Cxcl15Cxcl16Cxcl2CXCL3Cxcl5CXCL6CXCL9Cxcl17CXCL7
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