Recombinant Rat Fxn Protein, His-tagged
Cat.No. : | Fxn-1218R |
Product Overview : | Recombinant Rat Fxn Protein (41-208aa) was expressed in E. coli with N-terminal His-tag. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Rat |
Tag : | His |
Form : | Tris-based buffer, 50% glycerol. |
Molecular Mass : | 22.1 kDa |
AA Sequence : | LHVTANADAIRHSHLNLHYLGQILN IKKQSVCVVHLRNSGTLGNPSSLDE TAYERLAEETLDALAEFFED LADKPYTLKDYDVSFGDGVLTIKLG GDLGTYVINKQTPLLYLWFSGPCSG PKRYDWTGKNWVYSHDGVSL HELLARELTEALNTKLDLSSLAYSG KGT |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Storage : | The shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Gene Name : | Fxn frataxin [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Fxn |
Synonyms : | RGD1565754; Fxn; Frataxin, mitochondrial; EC 1.16.3.1; Frataxin intermediate form; Frataxin mature form |
Gene ID : | 499335 |
mRNA Refseq : | NM_001191952.1 |
Protein Refseq : | NP_001178881.1 |
UniProt ID : | D3ZYW7 |
Products Types
◆ Recombinant Protein | ||
FXN-1592R | Recombinant Rhesus Macaque FXN Protein, His (Fc)-Avi-tagged | +Inquiry |
FXN-275C | Recombinant Cynomolgus Monkey FXN Protein, His (Fc)-Avi-tagged | +Inquiry |
Fxn-3112M | Recombinant Mouse Fxn Protein, Myc/DDK-tagged | +Inquiry |
FXN-4576H | Recombinant Human FXN Protein, GST-tagged | +Inquiry |
FXN-3398M | Recombinant Mouse FXN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FXN-6108HCL | Recombinant Human FXN 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionFXN interacts with iron regulatory proteins, influencing cellular iron homeostasis by modulating the expression of genes involved in iron metabolism.
FXN deficiency increases cellular sensitivity to oxidative stress due to the disruption of iron homeostasis, leading to the accumulation of reactive oxygen species and cellular damage.
FXN assists in the formation of iron-sulfur clusters by providing a scaffold for the assembly of iron and sulfur atoms, promoting the stability and functionality of these clusters.
FXN influences cellular energy metabolism by supporting the function of iron-sulfur cluster-containing enzymes involved in key metabolic pathways, such as the tricarboxylic acid (TCA) cycle.
FXN deficiency results in impaired iron-sulfur cluster assembly, leading to mitochondrial dysfunction, oxidative stress, and ultimately causing Friedreich's ataxia.
Customer Reviews (3)
Write a reviewCustomer service was courteous and efficient, guiding us through the product selection process with expertise.
The consistent quality of this product has made it a staple in our lab, contributing to the success of various research projects.
Delivery was quick and hassle-free, allowing us to proceed with our experiments without any unnecessary delays.
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