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Recombinant Rat Fxn Protein, His-tagged

Cat.No. : Fxn-1218R
Product Overview : Recombinant Rat Fxn Protein (41-208aa) was expressed in E. coli with N-terminal His-tag.
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  • Gene Information
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Source : E. coli
Species : Rat
Tag : His
Form : Tris-based buffer, 50% glycerol.
Molecular Mass : 22.1 kDa
AA Sequence : LHVTANADAIRHSHLNLHYLGQILN IKKQSVCVVHLRNSGTLGNPSSLDE TAYERLAEETLDALAEFFED
LADKPYTLKDYDVSFGDGVLTIKLG GDLGTYVINKQTPLLYLWFSGPCSG PKRYDWTGKNWVYSHDGVSL
HELLARELTEALNTKLDLSSLAYSG KGT
Purity : Greater than 90% as determined by SDS-PAGE.
Storage : The shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Gene Name : Fxn frataxin [ Rattus norvegicus (Norway rat) ]
Official Symbol : Fxn
Synonyms : RGD1565754; Fxn; Frataxin, mitochondrial; EC 1.16.3.1; Frataxin intermediate form; Frataxin mature form
Gene ID : 499335
mRNA Refseq : NM_001191952.1
Protein Refseq : NP_001178881.1
UniProt ID : D3ZYW7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can you elaborate on the interactions between FXN and iron regulatory proteins in the cell? 04/26/2022

FXN interacts with iron regulatory proteins, influencing cellular iron homeostasis by modulating the expression of genes involved in iron metabolism.

What is the impact of FXN deficiency on the sensitivity of cells to oxidative stress? 01/23/2021

FXN deficiency increases cellular sensitivity to oxidative stress due to the disruption of iron homeostasis, leading to the accumulation of reactive oxygen species and cellular damage.

Can you explain the chemistry behind the iron-sulfur cluster assembly facilitated by FXN? 08/28/2020

FXN assists in the formation of iron-sulfur clusters by providing a scaffold for the assembly of iron and sulfur atoms, promoting the stability and functionality of these clusters.

How does FXN contribute to the regulation of cellular energy metabolism? 02/09/2019

FXN influences cellular energy metabolism by supporting the function of iron-sulfur cluster-containing enzymes involved in key metabolic pathways, such as the tricarboxylic acid (TCA) cycle.

How does FXN deficiency lead to Friedreich's ataxia on a molecular level? 04/05/2018

FXN deficiency results in impaired iron-sulfur cluster assembly, leading to mitochondrial dysfunction, oxidative stress, and ultimately causing Friedreich's ataxia.

Customer Reviews (3)

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Reviews
01/28/2021

    Customer service was courteous and efficient, guiding us through the product selection process with expertise.

    12/20/2019

      The consistent quality of this product has made it a staple in our lab, contributing to the success of various research projects.

      09/02/2018

        Delivery was quick and hassle-free, allowing us to proceed with our experiments without any unnecessary delays.

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