Recombinant Rat Glial Cell Derived Neurotrophic Factor

• Cat.No.: Gdnf-359R

Specification

• Species: Rat
• Source: Sf21 Cells
• Tag: Non
• Description: Glial cell derived neurotrophic factor, also known as GDNF is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily. GDNF potently promotes the survival of many types of neurons, most prominently, dopaminergic and motorneurons. GDNF regulates kidney development and spermatogenesis, and it affects alcohol consumption.
• Amino Acid Sequence: Ser78-Ile211.
• Molecular Weight: The predicted molecular weight of Recombinant Rat GDNF is Mr 15 kDa.
• State Of Matter: Lyophilized.
• Formulation: 0.2 μm filtered and lyophilized from a solution of Acetonitrile and TFA.
• Purity: >97% by SDS Page and analyzed by silver stain.
• Endotoxin: <0.1 ng per 1 µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: Gdnf glial cell derived neurotrophic factor [ Rattus norvegicus ]
• Synonyms: Gdnf; glial cell derived neurotrophic factor; Glial cell line derived neutrophic factor
• Gene ID: 25453
• mRNA Refseq: NM_019139
• Protein Refseq: NP_062012
• UniProt ID: Q07731
• Chromosome Location: q16
• Function: glial cell line-derived neurotrophic factor receptor binding; growth factor activity; protein homodimerization activity