Recombinant Rat GUCY2C Protein, His-tagged

• Cat.No.: GUCY2C-2743R
• Product Overview: Recombinant Rat GUCY2C Protein, fused to His-tag, was expressed in HEK293.

Specification

• Description: Enables guanylate cyclase activity and toxic substance binding activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to act upstream of or within regulation of cell population proliferation and response to toxic substance. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in congenital diarrhea 6. Orthologous to human GUCY2C (guanylate cyclase 2C).
• Source: HEK293
• Species: Human
• Tag: His
• Form: Supplied as a 0.2 μm filtered solution in PBS (pH 7.4).
• AA Sequence: SQVRQKCHNGTYEISVLMMDNSAYK EPLQNLRDAVEEGLDIVRKRLREAE LNVTVNATFIYSDGLIHKSGDCRSS TCEGLDLLREITRDRKMGCVLMGPS CTYSTFQMYLDTELNYPMISAGSFG LSCDYKETLTRILPPARKLMYFLVD FWKVNNAPFKTFSWNSSYVYKNGSE PEDCFWYLNALEAGVSYFSEVLSFK DVLRRSEQFQEILMGRNRKSNVIVM CGTPETFYNVKGDLKVADDTVVILV DLFSNHYFEDDTRAPEYMDNVLVLT LPPEKFIANASVSGRFPSERSDFSL AYLEGTLLFGHMLQTFLENGESVTT PKFARAFRNLTFQGLEGPVTLDDSG DIDNIMCLLYVSLDTRKYKVLMAYD THKNQTIPVATSPNFIWKNHRLPND VPGLGPQ
• Endotoxin: <1.0EU per 1ml (determined by the LAL method)
• Purity: >90%, by SDS-PAGE
• Storage: Short Term Storage at 4 centigrade. Long Term Storage at -20 centigrade to -80 centigrade. Avoid freeze/thaw cycles.
• Concentration: 1.0 mg/ml

Gene Information

• Gene Name: Gucy2c guanylate cyclase 2C [ Rattus norvegicus (Norway rat) ]
• Official Symbol: GUCY2C
• Synonyms: GCC
• Gene ID: 25711
• mRNA Refseq: NM_013170.1
• Protein Refseq: NP_037302.1
• UniProt ID: P23897