Recombinant Rat IL23a protein, His-SUMO-tagged

• Cat.No.: IL23a-3330R
• Product Overview: Recombinant Rat IL23a protein(Ala47~Ala196), fused with Two N-terminal Tags, His-tag and SUMO-tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Rat
• Tag: His&SUMO
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 25kDa
• Protein length: Ala47~Ala196
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Reconstitution: Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Il23a Interleukin 23, alpha subunit p19 [ Rattus norvegicus ]
• Official Symbol: IL23a
• Synonyms: IL23A; Interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin-23 subunit p19; MGC114275
• Gene ID: 155140
• mRNA Refseq: NM_130410
• Protein Refseq: NP_569094

Reviews

04/18/2020

Coupled with the manufacturer's exceptional technical support and commitment to customer satisfaction, researchers can confidently utilize the IL23A protein in their studies, knowing that they have the necessary resources and assistance to succeed.

12/02/2016

Its remarkable attributes and consistent results make it an indispensable tool in various experimental applications.

02/25/2016

Highly recommended for its exceptional performance in ELISA, the IL23A protein is a top contender for researchers involved in protein electron microscopy structure analysis.

Q&As

Is this bioactive cyno IL-23 heterodimer (p19/p40) or just the cyno IL-23p19 subunit?

Please inquiry our product manager with specific product.

Are there any FDA-approved drugs targeting IL23A?

Yes, drugs like ustekinumab and risankizumab, which target IL23A, have been approved for certain autoimmune diseases.

Is IL23A involved in the regulation of adaptive or innate immunity?

IL23A primarily plays a role in regulating the adaptive immune response.

How is IL23A linked to the pathogenesis of ankylosing spondylitis?

IL23A is associated with the inflammation of the spine and joints seen in ankylosing spondylitis, making it a target for therapeutic intervention.

How does IL23A contribute to rheumatoid arthritis?

In rheumatoid arthritis, IL23A is involved in the dysregulation of the immune system, leading to joint inflammation and damage.

How is IL23A involved in inflammatory bowel diseases like Crohn's disease?

IL23A is implicated in the pathogenesis of Crohn's disease, contributing to chronic inflammation in the gastrointestinal tract.