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Recombinant Rat Il23r protein, His & GST-tagged

Cat.No. : Il23r-1319R
Product Overview : Recombinant Rat Il23r aa. (Ile25~Leu355 (Accession # F1LX96) fused with N-terminal His & GST tag was produced in E. coli cells.
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  • Gene Information
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Source : E. coli
Species : Rat
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 68.0kDa.
Protein length : Ile25~Leu355 (Accession # F1LX96)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >90%
Characteristic : The isoelectric point is 8.4.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Il23r interleukin 23 receptor [ Rattus norvegicus (Norway rat) ]
Official Symbol : Il23r
Synonyms : Il23r; interleukin 23 receptor; interleukin 23 receptor; interleukin-23 receptor; interleukin 23 receptor-like
Gene ID : 689932
mRNA Refseq : XM_001072576.6
Protein Refseq : XP_001072576.3
UniProt ID : F1LX96

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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How does IL23R activation affect T-cell differentiation? 12/22/2022

IL23R activation promotes Th17 cell differentiation.

Does IL23R have alternative splicing variants? 02/20/2022

IL23R has multiple alternative splicing variants.

Does IL23R have any post-translational modifications that affect its stability? 08/23/2021

IL23R undergoes phosphorylation that affects its stability.

What is the half-life of IL23R protein in activated T-cells? 08/21/2020

The half-life of IL23R protein in activated T-cells is approximately 48 hours.

Are there any microRNAs that regulate IL23R expression? 06/16/2020

MicroRNAs like miR-20a regulate IL23R expression.

How does IL23R contribute to cytokine release? 02/15/2019

IL23R contributes to the release of pro-inflammatory cytokines like IL-17.

What role does IL23R play in autoimmune diseases? 08/22/2018

IL23R is implicated in autoimmune diseases like Crohn's.

How does IL23R expression change during infection? 10/12/2017

IL23R expression is upregulated during bacterial infection.

Does IL23R form homodimers or heterodimers? 08/15/2016

IL23R forms heterodimers with IL-12Rβ1.

What intracellular pathways are activated by IL23R? 08/06/2016

IL23R activates the JAK-STAT and NF-κB pathways.

Customer Reviews (3)

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Reviews
10/21/2020

    High specificity in ELISA.

    04/28/2016

      Effective in autoimmune models.

      03/30/2016

        Suitable for receptor binding studies.

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