Recombinant Rat Il23r protein, His & GST-tagged
|Product Overview :||Recombinant Rat Il23r aa. (Ile25~Leu355 (Accession # F1LX96) fused with N-terminal His & GST tag was produced in E. coli cells.|
- Gene Information
- Related Products
|Source :||E. coli|
|Tag :||His & GST|
|Form :||Freeze-dried powder|
|Molecular Mass :||Predicted Molecular Mass: 68.0kDa.|
|Protein length :||Ile25~Leu355 (Accession # F1LX96)|
|Endotoxin :||<1.0EU per 1µg (determined by the LAL method)|
|Characteristic :||The isoelectric point is 8.4.|
|Applications :||SDS-PAGE; WB; ELISA; IP.|
|Stability :||The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.|
|Storage :||Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.|
|Storage buffer :||Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.|
|Reconstitution :||Reconstitute in sterile PBS, pH7.2-pH7.4.|
|Gene Name :||Il23r interleukin 23 receptor [ Rattus norvegicus (Norway rat) ]|
|Official Symbol :||Il23r|
|Synonyms :||Il23r; interleukin 23 receptor; interleukin 23 receptor; interleukin-23 receptor; interleukin 23 receptor-like|
|Gene ID :||689932|
|mRNA Refseq :||XM_001072576.6|
|Protein Refseq :||XP_001072576.3|
|UniProt ID :||F1LX96|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (10)Ask a question
IL23R activation promotes Th17 cell differentiation.
IL23R has multiple alternative splicing variants.
IL23R undergoes phosphorylation that affects its stability.
The half-life of IL23R protein in activated T-cells is approximately 48 hours.
MicroRNAs like miR-20a regulate IL23R expression.
IL23R contributes to the release of pro-inflammatory cytokines like IL-17.
IL23R is implicated in autoimmune diseases like Crohn's.
IL23R expression is upregulated during bacterial infection.
IL23R forms heterodimers with IL-12Rβ1.
IL23R activates the JAK-STAT and NF-κB pathways.
Customer Reviews (3)Write a review
High specificity in ELISA. -
Effective in autoimmune models. -
Suitable for receptor binding studies. -
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