Recombinant Rat Interleukin 33 Il33-286R

Recombinant Rat Interleukin 33


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Recombinant Rat Interleukin 33

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Cat.No. : Il33-286R Optional Service: Optional requirements on this protein
Product Overview : Recombinant rat IL-33 (aa 109-264) was expressed in E. coli, ~16kDa.
Description : IL-33 is a new member of the IL-1 family. It is involved in T helper type 2 response via the activation of its receptor ST2 (IL-1RL1) driving the production of Th2-associated cytokines. The stimulation of ST2 by IL-33 induces the NF-κB and MAPK pathways. The human IL-33 protein is expressed with a prodomain (aa 1-111) which is cleaved by caspase-1 to produce the 18kDa mature protein (112-270).
Source : E. coli.
Purity : ≥95% (SDS-PAGE).
Concentration : 0.1mg/ml after reconstitution.
Formulation : Lyophilized. Contains PBS.
Endotoxin Content : <0.1EU/µg purified protein (LAL test; Bio Whittaker).
Reconstitution : Reconstitute with 100µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum.
Long Term Storage : -20°C.
Use/Stability : Stable for at least 6 months after receipt when stored at -20°C.
Handling : After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Gene Name : Il33 interleukin 33 [ Rattus norvegicus ]
Synonyms : interleukin 33; RGD1311155; Il33; interleukin-33; IL-33
Gene ID : 361749
mRNA Refseq : NM_001014166
Protein Refseq : NP_001014188
UniProt ID : Q66H70
Chromosome Location : 1q52
Pathway : Cytosolic DNA-sensing pathway
Function : cytokine activity; protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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