Recombinant Rat MINPP1 Protein (31-481 aa), His-tagged

• Cat.No.: MINPP1-654R
• Product Overview: Recombinant Rat MINPP1 Protein (31-481 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Full Length of Mature Protein.

Specification

• Description: Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification).
• Source: E. coli
• Species: Rat
• Tag: His
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 55.6 kDa
• Protein length: 31-481 aa
• AA Sequence: SLPGRGDPVASVLSPYFGTKTRYED VNPWLLGDPVAPRRDPELLAGTCTP VQLVALIRHGTRYPTTKQIRKLRQL QGLLQTRESVDGGSRVAAALDQWPL WYDDWMDGQLVEKGRQDMRQLALRL AALFPDLFCRENYGRLRLITSSKHR CVDSSAAFLQGLWQHYHPGLPPPDV SDMECDPPRVNDKLMRFFDHCEKFL TEVERNATALYHVEAFKTGPEMQTV LKKVAATLQVPVNNLNADLIQVAFF TCSFDLAIQGVHSPWCDVFDVDDAK VLEYLNDLKQYWKRSYGYAINSRSS CNLFQDIFLHLDKAVEQKQRSQPVS SSVILQFGHAETLLPLLSLMGYFKD KEPLTAYNFEEQVHREFRSGHIVPY ASNLIFVLYHCEDAQTPQEKFQIQM LLNEKVLPLAHSQKTVALYEDLKNH YQDILQSCQTSKECNLPKVNITSDE L
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: Minpp1 multiple inositol-polyphosphate phosphatase 1 [ Rattus norvegicus ]
• Official Symbol: MINPP1
• Synonyms: MINPP1; ins(1,3,4,5)P(4) 3-phosphatase
• Gene ID: 29688
• mRNA Refseq: NM_019263
• Protein Refseq: NP_062136
• UniProt ID: O35217