Recombinant Rat Nog Protein, His&GST-tagged

• Cat.No.: Nog-1834R
• Product Overview: Recombinant Rat Nog Protein (Met28-Cys144) with N-His&GST tag was expressed in E. coli.

Specification

• Description: Predicted to enable cytokine binding activity and protein homodimerization activity. Involved in several processes, including hippocampus development; learning or memory; and regulation of gliogenesis. Located in axon and extracellular space. Part of protein-containing complex. Biomarker of acute kidney tubular necrosis and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Huntington's disease; cleft lip; dysostosis (multiple); hyperopia; and proximal symphalangism (multiple). Orthologous to human NOG (noggin).
• Source: E. coli
• Species: Rat
• Tag: N-His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 43.6 kDa
  Accurate Molecular Mass: 44 kDa
• Protein length: Met28-Cys144
• Purity: > 90%
• Applications: Cell culture; Activity Assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Nog noggin [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Nog
• Synonyms: NOG; noggin
• Gene ID: 25495
• mRNA Refseq: NM_012990
• Protein Refseq: NP_037122
• UniProt ID: Q62809