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Recombinant Rat Smarca4 Protein, MBP/His-tagged

Cat.No. : Smarca4-36R
Product Overview : Recombinant Rat Smarca4 Protein, fused to MBP/His-tag, was expressed in E.coli.
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Description : Enables chromatin binding activity. Involved in negative regulation of transcription, DNA-templated; nucleosome disassembly; and spermatid development. Located in nucleus. Part of SWI/SNF complex. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 4; hepatocellular carcinoma; lung non-small cell carcinoma; and rhabdoid cancer. Orthologous to human SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4).
Source : E.coli
Species : Rat
Tag : MBP/His
Form : Liquid. In 1xPBS (pH 7.4).
Molecular Mass : 110.2 kDa
AA Sequence : MKIEEGKLVIWINGDKGYNGLAEVG KKFEKDTGIKVTVEHPDKLEEKFPQ VAATGDGPDIIFWAHDRFGGYAQSG LLAEITPDKAFQDKLYPFTWDAVRY NGKLIAYPIAVEALSLIYNKDLLPN PPKTWEEIPALDKELKAKGKSALMF NLQEPYFTWPLIAADGGYAFKYENG KYDIKDVGVDNAGAKAGLTFLVDLI KNKHMNADTDYSIAEAAFNKGETAM TINGPWAWSNIDTSKVNYGVTVLPT FKGQPSKPFVGVLSAGINAASPNKE LAKEFLENYLLTDEGLEAVNKDKPL GAVALKSYEEELAKDPRIAATMENA QKGEIMPNIPQMSAFWYAVRTAVIN AASGRQTVDEALKDAQTQYQIKGLE WLVSLYNNNLNGILADEMGLGKTIQ TIALITYLMEHKRINGPFLIIVPLS TLSNWAYEFDKWAPSVVKVSYKGSP AARRAFVPQLRSGKFNVLLTTYEYI IKDKHILAKIRWKYMIVDEGHRMKN HHCKLTQVLNTHYVAPRRLLLTGTP LQNKLPELWALLNFLLPTIFKSCST FEQWFNAPFAMTGEKVDLNEEETIL IIRRLHKVLRPFLLRRLKKEVEAQL PEKVEYVIKCDMSALQRVLYRHMQA KGVLLTDGSEKDKKGKGGTKTLMNT IMQLRKICNHPYMFQHIEESFSEHL GFTGGIVQGLDLYRASGKFELLDRI LPKLRATNHKVLLFCQMTSLMTIME DYFAYRGFKYLRLDGTTKAEDRGML LKTFNEPGSEYFIFLLSTRAGGLGL NLQSADTVIIFDSDWNPHQDLQAQD RAHRIGQQNEVRVLRLCTVNSVEEK ILAAAKYKLNVDQKVIQAGMFDQKS SSHERRAFLQAILEHEEQDEEEDEV PDDETVNQMIARHEEEFDLFMRMDL DRRREEARNPKRKPRLMEEDELPSW IIKDDAEVERLTCEEEEEKMFGRGS RHRKEVDYSHHHHHH
Purity : >90% as determined by SDS-PAGE
Storage : Short Term Storage at 4 centigrade, Long Term, please prepare aliquots with 20% glycerol and store at -20~-80 centigrade. Avoid freeze/thaw cycles.
Concentration : 0.21 mg/ml

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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