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Recombinant Rat THRA Protein

Cat.No. : THRA-6058R
Product Overview : Recombinant Rat THRA full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rat
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Thra thyroid hormone receptor alpha [ Rattus norvegicus ]
Official Symbol : THRA
Gene ID : 81812
mRNA Refseq : NM_001017960.1
Protein Refseq : NP_001017960.1
MIM :
UniProt ID : P63059

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Could the activity of THRA protein be harnessed to treat diseases? 06/29/2022

The activity of the THRA protein can be modulated by drugs or other small molecule compounds to treat diseases related to the THRA protein. For example, some drugs can inhibit the activity of the THRA protein to treat diseases such as hyperthyroidism.

How does the THRA protein relate to other hormones or signaling molecules? 10/22/2021

The THRA protein has some association with other hormones or signaling molecules. For example, it can interact with other hormones such as glucocorticoids and sex hormones to co-regulate the expression of target genes. In addition, it can interact with other signaling molecules, such as the MAPK signaling pathway.

How is THRA protein related to the initiation and progression of disease? 08/06/2020

Some studies have shown that abnormal expression of THRA protein may be related to the occurrence and progression of some diseases, such as thyroid disease, autoimmune diseases, etc. In addition, THRA proteins may also be drug targets for the treatment of these diseases.

What is the biological significance of THRA protein in humans? 06/22/2020

Biological significance of THRA protein in the human body is to regulate the physiological function of thyroid hormones. It can mediate its signal transduction through binding to thyroid hormones to maintain the body's metabolic balance and growth and development.

What are the interactions between THRA proteins and other nuclear receptors or proteins? 08/27/2019

Interaction between THRA proteins and other nuclear receptors or proteins is complex. For example, it can interact with other thyroid hormone receptors (THRB and THRG) to form heterodimers that co-regulate the expression of target genes. In addition, it can interact with regulatory factors, affecting their activity.

How is the activity of THRA protein regulated? 05/22/2019

Activity of THRA protein is regulated by a variety of factors, including the concentration of ligands (thyroid hormones), phosphorylation modifications, small molecule regulators, etc. These factors can affect the DNA binding capacity, transcriptional activation and ligand binding capacity of THRA proteins, thereby regulating their activity.

Customer Reviews (3)

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Reviews
08/18/2021

    The stability of THRA is highly appreciated, and its ability to maintain stable properties even after multiple freeze-thaw cycles is very valuable in practical applications.

    04/06/2021

      The short half-life and high clearance of THRA make it a promising candidate for new generation of therapeutic drugs.

      06/26/2020

        This production process of THRA is truly green and environmentally friendly, with little impact on the environment.

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