Recombinant Rat Timp1 Protein, His-tagged

• Cat.No.: Timp1-410R
• Product Overview: Recombinant Rat Timp1 Protein (Cys24-Ala217) with N-His tag was expressed in 293F.

Specification

• Description: Enables protease binding activity. Involved in several processes, including cartilage development; response to peptide hormone; and wound healing. Located in basement membrane. Used to study degenerative disc disease. Biomarker of cholestasis; gastric ulcer; heart disease (multiple); lung disease (multiple); and vascular disease (multiple). Orthologous to human TIMP1 (TIMP metallopeptidase inhibitor 1).
• Source: HEK293F
• Species: Rat
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 23.1 kDa
  Accurate Molecular Mass: 30 kDa
• Protein length: Cys24-Ala217
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Timp1 TIMP metallopeptidase inhibitor 1 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Timp1
• Synonyms: TIMP1; TIMP metallopeptidase inhibitor 1; metalloproteinase inhibitor 1; tissue inhibitor of metallopeptidase 1; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinases 1; Timp; TIMP-1
• Gene ID: 116510
• mRNA Refseq: NM_053819
• Protein Refseq: NP_446271
• UniProt ID: P30120