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Recombinant Rhesus macaque CD4 Protein, His-tagged

Cat.No. : CD4-158R
Product Overview : Recombinant Rhesus macaque CD4 protein with His tag was expressed in HEK293.
  • Specification
  • Gene Information
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Description : This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Source : HEK293
Species : Rhesus macaque
Tag : His
Form : Lyophilized
Molecular Mass : 42.3 kDa
Protein Length : 458
AA Sequence : MNRGIPFRHLLLVLQLALLPAVTQG KKVVLGKKGDTVELTCNASQKKNTQ FHWKNSNQIKILGIQGSFLTKGPSK LSDRADSRKSLWDQGCFSMIIKNLK IEDSDTYICEVENKKEEVELLVFGL TANSDTHLLEGQSLTLTLESPPGSS PSVKCRSPGGKNIQGGRTISVPQLE RQDSGTWTCTVSQDQKTVEFKIDIV VLAFQKASSTVYKKEGEQVEFSFPL AFTLEKLTGSGELWWQAERASSSKS WITFDLKNKEVSVKRVTQDPKLQMG KKLPLHLTLPQALPQYAGSGNLTLA LEAKTGKLHQEVNLVVMRATQFQEN LTCEVWGPTSPKLTLSLKLENKGAT VSKQAKAVWVLNPEAGMWQCLLSDS GQVLLESNIKVVPTWPTPVQPMALI VLGGVAGLLLFTGLGIFFCVRCRHR RRQAERMSQIKRLLSEKKTCQCPHR FQKTCSPI
Purity : > 98%
Applications : WB; ELISA; FACS; FC
Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
Storage : At -20 centigrade.
Concentration : 1 mg/mL
Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
Gene Name : CD4 CD4 molecule [ Macaca mulatta (Rhesus monkey) ]
Official Symbol : CD4
Synonyms : CD4; CD4 molecule; T-cell surface glycoprotein CD4; CD4 antigen; T-cell surface antigen T4/Leu-3;
Gene ID : 713807
mRNA Refseq : NM_001042662
Protein Refseq : NP_001036127
UniProt ID : P16003

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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