Recombinant Rhesus Macaque CXCR4 Protein, His (Fc)-Avi-tagged
Cat.No. : | CXCR4-940R |
Product Overview : | Recombinant Rhesus Macaque CXCR4 with His (Fc)-Avi tag was expressed and purified |
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Source : | HEK293 |
Species : | Rhesus Macaque |
Tag : | His&Fc&Avi |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | ≥85% by SDS-PAGE |
Stability : | Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | PBS buffer |
Gene Name : | CXCR4 chemokine (C-X-C motif) receptor 4 [ Macaca mulatta (Rhesus monkey) ] |
Official Symbol : | CXCR4 |
Synonyms : | CXCR4; C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; LESTR; SDF-1 receptor; fusin; leukocyte-derived seven transmembrane domain receptor; stromal cell-derived factor 1 receptor; |
Gene ID : | 707329 |
mRNA Refseq : | NM_001042645 |
Protein Refseq : | NP_001036110 |
UniProt ID : | H9ZDD5 |
Products Types
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThe responsive customer support team provided quick resolutions to any queries or issues we encountered.
The product's cost-effectiveness and clear instructions were instrumental in our experimental design.
We found the product's straightforward protocols highly conducive to seamless integration into our lab work.
Q&As (7)
Ask a questionCXCR4 participates in chemotaxis and migration of immune cells, facilitating their movement toward specific tissues during the immune response.
Specific chemokines or ligands, such as CXCL12, bind to CXCR4, influencing its role in immune cell activation and recruitment.
CXCR4 is predominantly localized on the cell surface of immune cells, particularly within the membrane of T cells and monocytes.
Dysregulation or abnormal expression of CXCR4 is associated with diseases such as cancer, HIV/AIDS, and autoimmune disorders, particularly affecting immune cell function.
There are potential therapeutic implications related to CXCR4 in diseases involving immune dysregulation and inflammation, making it a target for drug development.
CXCR4 contributes to the regulation of inflammatory responses and immune cell trafficking in various tissues, influencing the outcome of immune reactions.
C-X-C chemokine receptor type 4 (CXCR4) plays a crucial role in cellular processes, primarily contributing to immune responses and cell migration.
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