Recombinant Rhesus Macaque CXCR4 Protein, His (Fc)-Avi-tagged

Cat.No. : CXCR4-940R
Product Overview : Recombinant Rhesus Macaque CXCR4 with His (Fc)-Avi tag was expressed and purified
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Source : HEK293
Species : Rhesus Macaque
Tag : His (Fc)-Avi
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : ≥85% by SDS-PAGE
Stability : Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Storage Buffer : PBS buffer
Gene Name : CXCR4 chemokine (C-X-C motif) receptor 4 [ Macaca mulatta (Rhesus monkey) ]
Official Symbol : CXCR4
Synonyms : CXCR4; C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; LESTR; SDF-1 receptor; fusin; leukocyte-derived seven transmembrane domain receptor; stromal cell-derived factor 1 receptor;
Gene ID : 707329
mRNA Refseq : NM_001042645
Protein Refseq : NP_001036110
UniProt ID : H9ZDD5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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Reviews
04/07/2022

    The responsive customer support team provided quick resolutions to any queries or issues we encountered.

    10/28/2021

      The product's cost-effectiveness and clear instructions were instrumental in our experimental design.

      10/29/2018

        We found the product's straightforward protocols highly conducive to seamless integration into our lab work.

        Q&As (7)

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        How does CXCR4 participate in chemotaxis and migration of immune cells, particularly in the context of the immune response? 01/26/2022

        CXCR4 participates in chemotaxis and migration of immune cells, facilitating their movement toward specific tissues during the immune response.

        Are there specific chemokines or ligands that CXCR4 binds to, influencing its role in immune cell activation and recruitment? 01/09/2020

        Specific chemokines or ligands, such as CXCL12, bind to CXCR4, influencing its role in immune cell activation and recruitment.

        In which cellular compartments is CXCR4 predominantly localized, especially within immune cells? 06/14/2019

        CXCR4 is predominantly localized on the cell surface of immune cells, particularly within the membrane of T cells and monocytes.

        What diseases or conditions are associated with dysregulation or abnormal expression of CXCR4, especially in the immune system? 03/27/2019

        Dysregulation or abnormal expression of CXCR4 is associated with diseases such as cancer, HIV/AIDS, and autoimmune disorders, particularly affecting immune cell function.

        Are there therapeutic implications or potential targets related to CXCR4 in diseases involving immune dysregulation and inflammation? 06/28/2018

        There are potential therapeutic implications related to CXCR4 in diseases involving immune dysregulation and inflammation, making it a target for drug development.

        How does CXCR4 contribute to the regulation of inflammatory responses and immune cell trafficking in various tissues? 08/30/2017

        CXCR4 contributes to the regulation of inflammatory responses and immune cell trafficking in various tissues, influencing the outcome of immune reactions.

        What is the primary function of C-X-C chemokine receptor type 4 (CXCR4) in cellular processes and immune responses? 06/27/2016

        C-X-C chemokine receptor type 4 (CXCR4) plays a crucial role in cellular processes, primarily contributing to immune responses and cell migration.

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