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Recombinant Rhesus Macaque IGF1R Protein, His (Fc)-Avi-tagged

Cat.No. : IGF1R-2037R
Product Overview : Recombinant Rhesus Macaque IGF1R with His (Fc)-Avi tag was expressed and purified
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Source : HEK293
Species : Rhesus Macaque
Tag : His&Fc&Avi
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : ≥85% by SDS-PAGE
Stability : Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Storage Buffer : PBS buffer
Gene Name : IGF1R insulin-like growth factor 1 receptor [ Macaca mulatta (Rhesus monkey) ]
Official Symbol : IGF1R
Synonyms : IGF1R; insulin-like growth factor 1 receptor;
Gene ID : 708227
mRNA Refseq : NM_001261352
Protein Refseq : NP_001248281
UniProt ID : F7DLC9

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
07/08/2022

    The product's exceptional purity facilitated precise quantification, ensuring data consistency.

    06/14/2019

      The product consistently delivered robust and dependable results, affirming its efficacy in our experiments.

      04/29/2018

        The product's consistent performance bolstered the dependability of our research conclusions.

        Q&As (7)

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        In which cellular compartments is IGF1R predominantly localized? 04/06/2022

        IGF1R is predominantly localized on the cell membrane, where it acts as a receptor for insulin-like growth factors (IGFs) and insulin.

        Are there specific downstream signaling pathways activated by IGF1R, and how do they influence cell proliferation and survival? 04/27/2021

        Downstream signaling pathways activated by IGF1R include the Ras/MAPK pathway and PI3K/Akt pathway, contributing to cell growth and survival.

        How does IGF1R interact with insulin-like growth factors (IGFs) and insulin, and what is its role in growth regulation? 04/09/2020

        IGF1R interacts with IGFs and insulin, triggering downstream signaling pathways such as the PI3K/Akt pathway, influencing cell proliferation and survival.

        Are there therapeutic implications or potential targets related to IGF1R in diseases involving growth signaling? 09/06/2019

        There are potential therapeutic implications related to IGF1R in diseases involving growth signaling, making it a target for drug development.

        What diseases or conditions are associated with dysregulation or abnormal expression of IGF1R? 09/24/2018

        Dysregulation or abnormal expression of IGF1R is associated with conditions such as cancer and developmental disorders.

        What is the primary function of Insulin-like growth factor 1 receptor (IGF1R) in cellular processes and growth signaling? 10/03/2016

        Insulin-like growth factor 1 receptor (IGF1R) functions in cellular processes, primarily playing a role in growth signaling.

        How does IGF1R contribute to the regulation of tissue development, particularly in the context of growth and differentiation? 02/11/2016

        IGF1R contributes to the regulation of tissue development by influencing cell growth, differentiation, and survival.

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