| Description : |
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Source : |
HEK293 |
| Species : |
Rhesus macaque |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
41.3 kDa |
| Protein Length : |
234 |
| AA Sequence : |
VARHGAMCASGTLCCLALLCAASLG QRPTGGPGCGPGRLLLGTGKDARCC RVHPTRCCGDYQGEECCSEWDCVCV QPEFHCGNPCCTTCQHHPCPSGQGV QPQGKFSFGFRCVDCALGTFSRGHD GHCKPWTDCTQFGFLTVFPGNKTHN AVCVPGSPPAEPPGWLTIVLLAVAA CVLLLTSAQLGLHIWQLRKTQLLLE VPPSTEDASSCQFPEEERGERLAEE KGRLGDLWV |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
