Recombinant Rhesus macaque VTCN1 Protein, His-tagged


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Recombinant Rhesus macaque VTCN1 Protein, His-tagged

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Cat.No. : VTCN1-1519R
Product Overview : Recombinant Rhesus macaque B7-H4/VTCN1 Protein (Phe29-Ala258) with a C-His tag was expressed in human cells.
Description : B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
Source : Human Cells
Species : Rhesus macaque
Tag : His
Form : Lyophilized
Bio-activity : Immobilized Human GFRA1-His at 0.5µg/ml(100 µL/well) can bind Human GDNF. The ED50 of GDNF is 14.73 µg/mL.
Molecular Mass : 26.4 kDa
Endotoxin : < 1.0 EU per µg as determined by the LAL method.
Purity : > 95% as determined by reducing SDS-PAGE.
Applications : Immunogen
Storage : Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days.Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
Storage Buffer : Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Reconstitution : Please refer to the printed manual for detailed information.
Shipping : Ice packs.
Gene Name : VTCN1 V-set domain containing T cell activation inhibitor 1 [ Macaca mulatta (Rhesus monkey) ]
Official Symbol : VTCN1
Synonyms : VTCN1; V-set domain containing T cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1
Gene ID : 714123
mRNA Refseq : XM_001103715
Protein Refseq : XP_001103715
UniProt ID : F7B770
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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