Recombinant Rhesus Monkey CD276 Protein, hIgG4-tagged

• Cat.No.: CD276-1516R
• Product Overview: Recombinant Rhesus monkey CD276 Protein (XP_011709369 ( aa.29-540)) was expressed in human HEK293 cells with hIgG4 tag.

Specification

• Description: B7H3 participates in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
• Source: HEK293
• Species: Rhesus monkey
• Tag: hIgG4
• Form: PBS, pH7.4.
• Purity: > 95 %
• Applications: WB; ELISA; Immunogen
• Storage: -80 centigrade, Avoid freeze/thaw cycle.
• Concentration: 1 mg/mL

Gene Information

• Gene Name: CD276 CD276 molecule [ Macaca nemestrina (pig-tailed macaque) ]
• Official Symbol: CD276
• Synonyms: CD276; CD276 molecule; CD276 antigen; B7 H3; B7H3; B7RP 2; B7 homolog 3; costimulatory molecule; B7-H3; B7RP-2; 4Ig-B7-H3
• Gene ID: 105463777
• mRNA Refseq: XM_011711067.1
• Protein Refseq: XP_011709369