Recombinant Rhesus monkey CD59 protein, His & S-tagged
Cat.No. : | CD59-6833R |
Product Overview : | Recombinant Rhesus monkey CD59 aa. (His21~Leu107 (Accession # Q8SQ46)) fused with N-terminal His & S tag was produced in E. coli cells. |
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Source : | E. coli |
Species : | Rhesus monkey |
Tag : | His&S |
Form : | Freeze-dried powder |
Molecular Mass : | 20kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | His21~Leu107 (Accession # Q8SQ46) |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 5.8. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | CD59 CD59 molecule (CD59 blood group) [ Macaca mulatta (Rhesus monkey) ] |
Official Symbol : | CD59 |
Synonyms : | CD59 glycoprotein preproprotein; Membrane attack complex inhibition factor; CD59 glycoprotein |
Gene ID : | 693402 |
mRNA Refseq : | NM_001261705.1 |
Protein Refseq : | NP_001248634.1 |
UniProt ID : | Q8SQ46 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThe quality is very high and the reliability is very helpful for our research results.
There are no doping impurities, the experimental effect is very good, and I will recommend it to other students.
Easy to operate and cost-effective.
Q&As (6)
Ask a questionIn hemolytic diseases, the deficiency or dysfunction of CD59 may lead to excessive lysis of red blood cells because the formation of the complement C5b-9 complex cannot be effectively prevented.
Yes, the expression level of CD59 can vary in different cell types. In general, it is expressed higher in blood cells and some tumor cells.
When researching CD59, laboratories may encounter technical challenges such as selecting the appropriate assay, ensuring the quality and consistency of samples, and the complexity of interpreting results. In addition, CD59 expression variations in different cell types and experimental conditions need to be considered.
Aberrant expression of CD59 has been associated with a variety of diseases, including but not limited to hemolytic diseases, certain types of cancer, and autoimmune diseases.
CD59 expression can be detected using flow cytometry, immunofluorescence staining, or western blotting.
The current treatment for CD59 is still in the research stage, and there is no drug approved for clinical use. However, some studies are exploring the use of gene therapy or antibody therapy to modulate CD59 expression or function.
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