Recombinant Rhesus Monkey FZD4 Protein, hIgG4-tagged

• Cat.No.: FZD4-1766R
• Product Overview: Recombinant Rhesus monkey FZD4 Protein (NP_001253804 ( aa.37-222)) was expressed in human HEK293 cells with hIgG4 tag.

Specification

• Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin (CTNNB1) canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin (CTNNB1) and activation of Wnt target genes. Plays a critical role in retinal vascularization by acting as a receptor for Wnt proteins and norrin (NDP).
• Source: HEK293
• Species: Rhesus monkey
• Tag: hIgG4
• Form: PBS, pH7.4.
• Purity: > 95 %
• Applications: ELISA; WB; Immunogen
• Storage: -80 centigrade, Avoid freeze/thaw cycle.
• Concentration: 1 mg/mL

Gene Information

• Gene Name: FZD4 frizzled class receptor 4 [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: FZD4
• Synonyms: FZD4; frizzled family receptor 4; EVR1; exudative vitreoretinopathy 1 ; frizzled (Drosophila) homolog 4 ; frizzled 4; seven transmembrane spanning receptor ; frizzled homolog 4 (Drosophila); frizzled-4; CD344; hFz4; frizzled homolog 4; WNT receptor frizzled-4; frizzled 4; seven transmembrane spanning receptor; EVR1; FEVR; Fz-4; FzE4; GPCR; FZD4S; MGC34390
• Gene ID: 704754
• mRNA Refseq: NM_001266875.1
• Protein Refseq: NP_001253804