Recombinant Rhesus monkey INSIG2 Protein, His-tagged

• Cat.No.: INSIG2-2279R
• Product Overview: Recombinant Rhesus monkey INSIG2 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Rhesus monkey
• Tag: His
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: INSIG2 insulin induced gene 2 [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: INSIG2
• Synonyms: INSIG2; insulin-induced gene 2 protein
• Gene ID: 693654
• mRNA Refseq: NM_001194781
• Protein Refseq: NP_001181710
• UniProt ID: F7HBW1

Reviews

08/16/2020

We observed that results obtained with the product remained stable and reliable over long-term experiments.

01/11/2020

The product's impact extended to data analysis, with intuitive tools for interpreting experimental results.

07/07/2017

Its adaptability to various sample types and conditions made it a valuable asset for our diverse projects.

Q&As

Are there any post-translational modifications known to regulate INSIG2?

While specific post-translational modifications may exist, the current literature provides limited information on post-translational regulation of INSIG2.

How does INSIG2 contribute to insulin sensitivity?

INSIG2 contributes to insulin sensitivity by regulating lipid metabolism and insulin signaling pathways.

How does INSIG2 impact the activity of SREBP-1 and SREBP-2?

INSIG2 inhibits the activity of both SREBP-1 and SREBP-2, impacting lipogenesis and cholesterol biosynthesis.

What is the relationship between INSIG2 and cholesterol synthesis?

INSIG2 is a key regulator of cholesterol synthesis, modulating the activation of SREBP-2, a master regulator of cholesterol biosynthesis.

What is the role of INSIG2 in cellular response to ER stress?

INSIG2 is involved in the cellular response to ER stress, playing a role in maintaining ER homeostasis.

Is there evidence of INSIG2 involvement in cancer development?

There is evidence linking INSIG2 to cancer development, suggesting a potential role in tumorigenesis.

Does INSIG2 expression vary in response to different dietary conditions?

Yes, INSIG2 expression can vary in response to different dietary conditions, reflecting its role in metabolic adaptation.