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Recombinant Rhesus monkey TOP1 Protein, His-tagged

Cat.No. : TOP1-4899R
Product Overview : Recombinant Rhesus monkey TOP1 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rhesus monkey
Tag : His
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : TOP1 topoisomerase (DNA) I [ Macaca mulatta (Rhesus monkey) ]
Official Symbol : TOP1
Synonyms : TOP1; DNA topoisomerase 1;
Gene ID : 697300
mRNA Refseq : NM_001266512
Protein Refseq : NP_001253441
MIM :
UniProt ID : H9FZ51

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the role of TOP1 in the repair of DNA damage caused by environmental factors and chemotherapeutic agents? 12/01/2021

TOP1 repairs DNA damage, maintaining genomic stability under stress.

How do post-translational modifications of TOP1, such as phosphorylation, affect its enzymatic activity and interaction with DNA? 07/17/2021

Post-translational modifications like phosphorylation affect TOP1's activity and DNA interaction.

How do mutations in the TOP1 gene contribute to genomic instability and the development of certain cancers? 02/28/2021

Mutations in TOP1 cause genomic instability, increasing cancer risk.

What are the effects of TOP1 inhibitors on cancer cell proliferation and survival? 12/12/2019

TOP1 inhibitors lead to cancer cell death and inhibit tumor growth by disrupting DNA processes.

How does TOP1 interact with other proteins in the DNA repair and replication machinery? 09/22/2019

TOP1 works with other DNA repair proteins, ensuring accurate DNA synthesis.

How does TOP1 regulate DNA unwinding and re-ligation during transcription and replication? 09/20/2019

TOP1 regulates DNA unwinding by creating transient breaks, aiding transcription and replication.

What are the implications of TOP1 expression levels in predicting the response to chemotherapy in cancer patients? 09/17/2018

TOP1 expression levels predict chemotherapy responses in cancer treatment.

Customer Reviews (3)

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Reviews
10/17/2019

    Accurate protein structural analysis; a key for structural biology.

    10/06/2018

      High-quality protein crystallography; essential for structural biology.

      05/30/2018

        Timely protein characterization; vital for our research projects.

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