Recombinant Saccharomyces cerevisiae SNF2 Protein, His-tagged

• Cat.No.: SNF2-74S
• Product Overview: Recombinant Saccharomyces cerevisiae SNF2 Protein, fused to His-tag, was expressed in E. coli.

Specification

• Species: S.cerevisiae
• Source: E.coli
• Tag: His
• Description: Enables several functions, including ATP-dependent chromatin remodeler activity; DNA binding activity; and lysine-acetylated histone binding activity. Involved in several processes, including DNA metabolic process; nucleosome mobilization; and positive regulation of cell adhesion involved in single-species biofilm formation. Located in nucleus. Part of SWI/SNF complex. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 4; hepatocellular carcinoma; lung non-small cell carcinoma; and rhabdoid cancer. Orthologous to human SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2) and SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4).
• Form: Supplied as a 0.2 μm filtered solution in PBS (pH 7.4).
• Molecular Mass: ~91 kDa
• AA Sequence: MKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTIEGRMNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFANTGGQDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLFIGDQNNKKMVGLRGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPAQALQAQDRAHRIGQKNEVRILHHHHHH
• Purity: >90%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.1 mg/ml
• Official Full Name: SWI/SNF catalytic subunit SNF2

Gene Information

• Gene Name: SNF2 SWI/SNF catalytic subunit SNF2 [ Saccharomyces cerevisiae S288C ]
• Official Symbol: SNF2
• Synonyms: GAM1; HAF1; SWI2; TYE3
• Gene ID: 854465
• mRNA Refseq: NM_001183709
• Protein Refseq: NP_014933
• UniProt ID: P22082