Recombinant SARS-Associated Coronavirus Spike Mosaic S(M) Protein

• Cat.No.: Mosaic-771C
• Product Overview: SARS-ACSM contains the middle section of the Spike protein immunodominant fragments, amino acids: 408-470, 540-573. SARS-ACSM is purified by proprietary chromatographic techniques.

Specification

• Species: Coronavirus
• Source: E.coli
• Tag: Non
• Description: The spike (S) glycoprotein of coronaviruses mediates viral entry into host cells. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. It is a type 1 viral fusion protein that characteristically contains two heptad repeat regions, denoted HR-N and HR-C, that form coiled-coil structures within the ectodomain of the protein. Previous studies have shown that the two heptad repeat regions can undergo a conformational change from their native state to a 6-helix bundle (trimer of dimers), which mediates fusion of viral and host cell membranes .
• Form: 25 mM Tris-HCl, 0.4% sarcosyl, 0,25% Triton X-100 and 50% glycerol
• Molecular Mass: 38 kDa
• Purity: > 95 % (SDS-PAGE)
• Applications: ELISA; Western Blot
• Storage: Store at -20 centigrade, avoid freeze/thaw cycles.

Gene Information

• Official Symbol: Mosaic
• Synonyms: Mosaic