Recombinant SARS-CoV-2 Nucleocapsid phosphoprotein, His-tagged

• Cat.No.: N-129V
• Product Overview: Recombinant SARS-CoV-2 Nucleocapsid phosphoprotein (1-419aa) was fused to His-tag at C-terminus and expressed and purified from E.coli.

Specification

• Species: SARS-CoV-2
• Source: E.coli
• Protein Length: 419
• Description: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
• Form: Liquid. 25mM Tris base, 10mM K2CO3.
• Molecular Mass: 48 kDa
• Purity: 95% purity (10% SDS-PAGE, coomassie blue staining).
• Storage: -20 centigrade.
• Concentration: 2.4 mg/ml
• Shipping: Dry Ice.
• Warning: Avoid multiple freeze-thaw cycles. For Research Use Only.

Gene Information

• Gene Name: N
• Official Symbol: N
• Synonyms: GU280_gp10
• Gene ID: 43740575
• Protein Refseq: YP_009724397.2