Recombinant SARS-CoV-2 S Protein, Fc/Avi-tagged
| Cat.No. : | S-002S |
| Product Overview : | Severe acute respiratory Coronavirus 2 Spike Glycoprotein S1 (SARS-CoV-2 Spike S1), a.a. 16-685, fused at the C-terminus of the Fc portion of human IgG1, with a C-terminal Avi-tag™, expressed in a HEK293 expression system. |
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- Gene Information
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| Description : | Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 and CLEC4M/DC-SIGNR receptors and internalization of the virus into the endosomes of the host cell induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes. |
| Source : | HEK293 |
| Species : | SARS-CoV-2 |
| Tag : | Fc/Avi |
| Molecular Mass : | 104 kDa |
| Protein length : | 16-685 |
| Purity : | ≥ 90% |
| Applications : | Enzyme kinetics, screening inhibitors, and selectivity profiling |
| Stability : | ≥ 6 months |
| Storage : | Store at -80 centigrade |
| Storage Buffer : | 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol |
| Warning : | Avoid freeze/thaw cycles |
| Gene Name : | S spike glycoprotein [ SARS coronavirus Tor2 ] |
| Official Symbol : | S |
| Synonyms : | S; spike glycoprotein; E2; spike glycoprotein |
| Gene ID : | 1489668 |
| UniProt ID : | P59594 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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