Recombinant SARS-CoV Spike S1 Protein, His-tagged

• Cat.No.: S-199S
• Product Overview: Recombinant SARS-CoV Spike Protein S1 (14-680) was expressed in CHO cells using a C-terminal His tag.

Specification

• Species: SARS-CoV
• Source: CHO
• Tag: His
• Protein Length: 14-680
• Description: The severe acute respiratory syndrome related novel coronavirus (SARS-CoV) has caused the 2002-2003 SARS epidemic that broke out in southern China, which spread to other regions of Asia, Europe and North America. The spike glycoprotein (S) of coronavirus belongs to the type I transmembrane protein containing two subunits, S1 and S2, which is also known to be the key component to bind with host cells through the interaction with angiotensin-converting enzyme 2 (ACE2). SARS-CoV can specifically recognize ACE2 through its receptor binding domain (RBD) of S1 to initiate viral infection in humans.
• Molecular Mass: 125 kDa
• Purity: >90%
• Applications: ELISA
• Storage: Store product at –70 centigrade. For optimal storage, aliquot targets into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 μg/μL
• Storage Buffer: Recombinant protein stored in 50mM sodium phosphate, pH 7.5, 300mM NaCl, 150mM imidazole.

Gene Information

• Gene Name: S spike glycoprotein [ SARS coronavirus Tor2 ]
• Official Symbol: S
• Synonyms: S; spike glycoprotein; E2
• Gene ID: 1489668
• Protein Refseq: NP_828851
• UniProt ID: P59594