Recombinant Swine IL15

• Cat.No.: IL15-263S
• Product Overview: Swine IL-15 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.

Specification

• Species: Pig
• Source: Yeast
• Tag: Non
• Description: Interleukin 15 (IL-15) is a cytokine with structural similarity to IL-2 that is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells. IL-15 was discovered to be a member of a family of cytokines, which also includes IL-2, IL-4, IL-7, IL-9, and IL-21. The specific receptor for IL-15, IL-15 receptor alpha, appears to regulate IL-15 secretion, stability, and activity. All members of this family use the common gamma chain as part of their signaling complex. IL-15 has been shown to play a role in many diseases, including obesity, influenza, and inflammatory autoimmune diseases.
• Form: Lyophilized without carrier protein.
• Molecular Mass: Swine IL-15 has a predicted molecular weight of 13.1 kDa.
• AA Sequence: TWQHVISDLK KIEDLIRSIH MDATLYTESD AHPNCKVTAM KCFLLELRVI LQESRNSDIS DTVENLIILA NSSLSSIEYK TESGCKECEE LEEKNINEFL KSFIHIVQMF INPS (114)
• Purity: >95% as visualized by SDS-PAGE analysis.
• Applications: The Swine IL-15 protein can be used in cell culture, as an IL-15 ELISA Standard, and as a Western Blot Control.
• Storage: Stable for up to twelve months from date of receipt at -20ºC. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20ºC. Avoid repeated freeze/thaw cycles.
• Reconstitution: Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.

Gene Information

• Gene Name: IL15 interleukin 15 [ Sus scrofa (pig) ]
• Official Symbol: IL15
• Synonyms: IL15; interleukin 15; IL-15; interleukin-15
• Gene ID: 397683
• mRNA Refseq: NM_214390
• Protein Refseq: NP_999555
• UniProt ID: Q95253
• Chromosome Location: 8; 8
• Pathway: Cytokine-cytokine receptor interaction; HTLV-I infection; HTLV-I infection
• Function: cytokine activity; cytokine receptor binding