Recombinant Swine KITLG Protein
Cat.No. : | KITLG-4355S |
Product Overview : | Recombinant Swine KITLG Protein (166aa) was expressed in yeast. |
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- Specification
- Gene Information
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Source : | Yeast |
Species : | Swine |
Form : | Lyophilized |
Molecular Mass : | 18.7 kDa |
Protein length : | 166aa |
AA sequence : | QGICRNRVTD DVKDVTKLVA NLPKDYKITL KYVPGMDVLP SHCWISEMVE QLSVSLTDLL DKFSNISEGL SNYSIIDKLV KIVDDLVECM EEHSFENVRK SSKSPEPRLF TPEKFFGIFN RSIDAFKDLE MVAPKTSECV ISSTLTPEKD SRVSVTKPFM LPPVAA (166) |
Purity : | >95% as visualized by SDS-PAGE analysis. |
Applications : | This endotoxin-free recombinant protein can be used in cell culture, ELISA Standard, and as a Western Blot Control. |
Storage : | Store at -20 centigrade. |
Gene Name : | KITLG KIT ligand [ Sus scrofa (pig) ] |
Official Symbol : | KITLG |
Synonyms : | KITLG; KITL; KIT ligand protein; MGF; SCF; c-kit ligand |
Gene ID : | 397509 |
mRNA Refseq : | NM_214269.2 |
Protein Refseq : | NP_999434.2 |
Products Types
◆ Recombinant Protein | ||
Kitl-3698M | Active Recombinant Mouse Kitl Protein | +Inquiry |
Kitl-1713M | Recombinant Mouse Kitl Protein, His-tagged | +Inquiry |
KITLG-217H | Active Recombinant Human KITLG Protein (Glu26-Ala189), C-His tagged, Animal-free, Carrier-free | +Inquiry |
Kitl-151K | Active Recombinant Mouse Kitl Protein (165 aa) | +Inquiry |
Kitlg-4827M | Recombinant Mouse Kitlg Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
KITLG-583MCL | Recombinant Mouse KITLG cell lysate | +Inquiry |
KITLG-571HCL | Recombinant Human KITLG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionOverexpression or mutations in KITLG and its receptor have been implicated in various cancers, including gastrointestinal stromal tumors (GISTs), mastocytosis, and certain leukemias.
Given its role in cell proliferation and differentiation, KITLG has been explored as a therapeutic agent in stem cell transplantation settings, and its pathway is a target in certain cancer treatments.
Dysregulation or mutations in KITLG have been associated with certain disorders like piebaldism, a genetic condition characterized by unpigmented patches of skin and hair.
Upon binding to c-KIT, KITLG activates the SCF signaling pathways, which include the MAPK, PI3K, and JAK/STAT pathways, influencing cell survival, proliferation, and differentiation.
KITLG binds to the c-KIT receptor, a tyrosine kinase receptor, leading to its dimerization and autophosphorylation, which activates downstream signaling pathways.
Given its role in cell proliferation and differentiation, KITLG has been explored as a therapeutic agent in stem cell transplantation settings, and its pathway is a target in certain cancer treatments.
KITLG and its receptor c-KIT are involved in melanogenesis. Their interaction regulates the proliferation and migration of melanocytes, influencing skin, hair, and eye pigmentation.
Customer Reviews (3)
Write a reviewReliable for immunoprecipitation assay.
No contamination, very clean.
Worked perfectly in Western.
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